Results 231 to 240 of about 2,107,565 (334)

Comparing the Efficacy of Myosin Inhibition Versus Thin Filament Calcium Desensitization for Treatment of Pediatric Restrictive Cardiomyopathy Using a Patient-Derived hiPSC Model. [PDF]

Circ Genom Precis Med
Staudt DW, Serrano R, Hnatiuk AP, Sanchez I, Carhuamaca X, Feyen DAM, Mercola M.   +6 more
europepmc   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

Long-Term Clinical Outcomes of ABO-Incompatible Kidney Transplantation in Patients With High Baseline Anti-A/B Antibody Titers. [PDF]

J Korean Med Sci
Eum SH, Lee H, Ko EJ, Min JW, Ban TH, Yoon HE, Shin SJ, Chung BH.   +7 more
europepmc   +1 more source

Desensitization in HLA-incompatible kidney recipients and survival.

New England Journal of Medicine, 2011
R. Montgomery, B. Lonze, K. King, E. Kraus, L. Kucirka, J. Locke, D. Warren, C. Simpkins, N. Dagher, A. Singer, A. Zachary, D. Segev   +11 more
semanticscholar   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Clinical outcome of Nd:YAG laser and bioactive glass combined use for dentin hypersensitivity after scaling and root planning: a short-term comparative study. [PDF]

Eur J Med Res
Yan K, Si W, Guo J, Liu J, Zheng Y, Hou X, Fan S.   +6 more
europepmc   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Elagolix as a Diagnostic and Therapeutic Bridge to Surgery in Refractory Progestogen Hypersensitivity. [PDF]

JCEM Case Rep
Balkan AO, Sistla D, Rhinehart EL.
europepmc   +1 more source

An investigation into the development of mental toughness in the British Army [PDF]

, 2014
Newell, Adrian, Rayner, Charlotte Ann Louise   +1 more
core   +1 more source

A Risk or a Buffer? The Dual Role of Poverty in Community Perceptions of Child Protection Demand

Child &Family Social Work, EarlyView.
ABSTRACT The relationship between poverty and child protection demand is complex. Using macro‐level data from 293 Finnish municipalities, this study applies hierarchical linear regression and mediation analysis to examine how poverty shapes community perceptions of child protection demand. The hierarchical linear regression findings reveal that poverty
Ning Zhu, Juulia Hietamäki, Aleksandra Gawel, Timo Toikko   +3 more
wiley   +1 more source