Results 31 to 40 of about 1,435,660 (290)

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Arquitetura, desenvolvimento e diversidade dos Metazoários: exercício 2

, 2016
Ensino Médio::BiologiaAprsenta exercício interativo que convida o aluno a testar seus conhecimentos sobre o desenvolvimento das células ...
Portugal. Ministério da Educação. Direcção-Geral de Inovação e de Desenvolvimento Curricular (DGIDC)
core   +2 more sources

Ferroionic Electrostatic Landscapes Enabling Wireless Energy Harvesting, Storage, and Sensing

Advanced Electronic Materials, EarlyView.
By integrating experiments and electrostatic field simulations, we show that long‐range wireless coupling in Li‐based ferroionics devices emerges from the cooperative interaction between ionic migration and electronic polarization. This coupling sustains self‐polarized electrostatic fields across centimeter‐scale air gaps without external bias or ...
M. Helena Braga, Beatriz M. Gomes, António B. Vale, Beatriz A. Maia, Ilídio B. Costa, Filipa Braz, Jorge C. Ribeiro, João C. Ribeiro   +7 more
wiley   +1 more source

Engineering a Correlated Narrow‐Gap Semiconductor: Effects of Ga Substitution in EuZn2P2

Advanced Electronic Materials, EarlyView.
ABSTRACT The effect of Ga substitution on the electronic, magnetic, and low‐energy responses of the Zintl phase EuZn2P2${\rm EuZn}_2 {\rm P}_2$ is investigated by electrical transport, electron spin resonance (ESR), and terahertz time‐domain spectroscopy (THz‐TDS). Incorporating Ga into EuZn2P2${\rm EuZn}_2 {\rm P}_2$ (EuZn1.8Ga0.2P2${\rm EuZn}_{1.8} {\
Mateus Dutra, Esteban Marulanda, Gustavo G. Vasques, Jaime Ferreira Oliveira, Pedro C. Sabino, Rebeca Brigato Delgado, Leticie Mendonça‐Fereira, Adriano R. V. Benvenho, Elisa Baggio‐Saitovitch, Ricardo K. Machado, Nicolas M. Kawahala, Julian Munevar, Marcos A. Avila, Felix G. G. Hernandez   +13 more
wiley   +1 more source

Avanços na compreensão da relação entre temperamento e comportamento anti-social

INFAD, 2015
Este artigo constitui uma síntese compreensiva de contributos teóricos e empíricos acerca da relação entre o temperamento e o comportamento anti-social.
Sonia Mairos Ferreira
doaj   +1 more source

One‐Step Synthesis of Size‐Controlled Copper Oxide Nanoparticles on Laser‐Induced Graphene Sensor for L‐Cysteine Detection

Advanced Electronic Materials, EarlyView.
Oxygen plasma treatment enhances polyimide hydrophilicity and promotes uniform anchoring of copper ion precursors. A one‐step laser process then generates CuO‐decorated nanoparticles on laser‐induced graphene (LIG) electrodes, enabling controlled nanoparticle growth via precursor concentration tuning.
Gustavo Miguel Sousa, Ketley Caroline Rocha Pereira, Deissy Johanna Feria Garnica, Marcos Rocha Diniz da Silva, Matheus Santos Dias, Camila Marchetti Maroneze, Cecilia de Carvalho Castro Silva   +6 more
wiley   +1 more source

Jogo de bancos de desenvolvimento

, 1968
BNDE/MIT Joint Development Bank Training and Research.The Grupo de Trabalho Misto is the working entity carrying on the goals of the BNDE/MIT Joint Development Bank Training and Research Project. The Project was created in 1967 with the support of a Ford
Massachusetts Institute of Technology, Senior, Colin, Nyhart, J. D.   +2 more
core   +1 more source

Ficha Técnica da Edição

Desenvolvimento e Meio Ambiente
Equipe Editorial e Técnica deste volume / Editorial and technical team for this volume:   Editores-chefes / Editors-in-chief: Manuela Dreyer Silva e Letícia da Costa e Silva Editores adjuntos / Associate editors: Angela Duarte Damasceno Ferreira,
Editores Desenvolvimento e Meio Ambiente
doaj   +1 more source

O problema contemporâneo do desenvolvimento: situação presente e antecedentes históricos

Revista de História, 1969
O tema desta aula foi escolhido com o propósito de expôr e ilustrar o ponto de vista de que a história econômica pode constituir um instrumento complementar de análise dos fenômenos contemporâneos de caráter econômico, em particular daqueles de mais ...
Nuno Fidelino de Figueiredo
doaj   +1 more source