Results 61 to 70 of about 1,811,176 (286)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

MICROMORPHOLOGY AND PHYTOCHEMICAL SCREENING OF OPUNTIA LITTORALIS ENGLEM. CLADODES [PDF]

Egyptian Journal of Desert Research, 2017
The present study was conducted to investigate the micromorphological structure and phytochemical constituents of Opuntia littoralis stem (cladodes) growing at the western Mediterranean coast of Egypt.
Tarek Galal, Loutfy Hassan, Adel Youssef, Heba Abd El-Moaty, Hanaa Gouda   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

POTENTIAL OF SALICORNIA FRUTICOSA AS A FORAGE IN EGYPT: PHYTOCHEMICAL CONSTITUENTS, NUTRITIVE VALUE, AND METHANE PRODUCTION (AN IN VITRO PRELIMINARY STUDY) [PDF]

Egyptian Journal of Desert Research
This study was carried out to investigate the potential of different ecotypes of Salicornia fruticosa to be a forage crop for ruminants. Three different ecotypes of Salicornia as wild, monoculture and intercropped (with tomato plants) were tested in ...
Moustafa Ghandour, Fatma Ahmed, Islam Wassif, Waleed Fahmy, Salah Abo Bakr Abo Bakr, Mohamed Badawy, Hassan El Shaer   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

The Optimized Method of Agrobacterium Mediated Transformation in Nitraria schoberi (Ghar-e-Dagh in Persian) [PDF]

Journal of Genetic Resources, 2019
Ghar-e-Dagh (Nitraria schoberi) is a native perennial plant profoundly resistant to salinity and drought. This plant, having a well-developed deep rooting system can act as sand dunes stabilization agent and also, due to its special alkaloids may perform
Fatemeh Eskandari, Mohammad Ali Ebrahimi, Hamid Reza Naseri, Nasim Zarinpanjeh   +3 more
doaj   +1 more source

Wetland Plants in the Desert

Carnivorous Plant Newsletter, 2003
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Salvia, Elizabeth M., Rice, Barry A.
openaire   +2 more sources

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Effect of different planting locations in Egypt on volatile oil of geranium (Pelargonium graveolens L.) plant

Journal of Basic and Applied Research in Biomedicine, 2022
This work was carried out during the two successive seasons (2012/2013 and 2013/2014) to investigate the effect of different planting locations on quantity and quality of Pelargnium graveolens L. volatile oil.
M Abd El-Wahab, W Toaima, E Hamed
doaj