Results 61 to 70 of about 22,605 (200)
Desferrioxamine, An Iron Chelator, Induces CXCL8 Expression in U373MG Human Astrocytoma Cells [PDF]
Dysregulation of iron homeostasis in brain causes various neurodegenerative disorders. In fact, high concentration of iron is present in brains of patients with Alzheimer’s disease.
Xing, Fei +8 more
core +1 more source
Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report [PDF]
, 2004 We describe a case of a female who developed haemosiderosis, in the course of treatment for very severe unstable aplastic anaemia for fourteen years. She was 37 years old at the time of initial diagnosis.
Mwanda, OW, Otieno, CF, Abdalla, FK
core +1 more source
Quality of life in transfusion-dependent thalassaemia patients on desferrioxamine treatment
, 2009 Optimum desferrioxamine usage reduces iron overload complications and provides a better quality of ...
Dahlui, M. +3 more
core +1 more source
Survival and desferrioxamine in thalassaemia major.
, 2016 A small randomised trial and observation of all patients homozygous for beta-thalassaemia in Britain born in or before 1963 indicated that those patients who had received average weekly doses of more than 4 g of desferrioxamine over the previous few ...
core
Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo.
, 1994 Vascular smooth muscle cell (VSMC) growth is a primary component of accelerated and spontaneous atherosclerosis. Previous studies have shown that iron may be involved in the control of enzymatic activities that modulate DNA synthesis in human cells.
S Ucchino +7 more
core +1 more source
Journal of Mazandaran University of Medical Sciences, 2007 Background and Purpose: Cardiac complications in major thalassemia are the most debilitating problem among them. Iron chelating with desferrioxamine, may be difficult or inadequate.
F. Rashidi ghader, M.D +2 more
doaj
Adverse effects of a modified regime of intravenous desferrioxamine
, 2014 The aim of this study was to investigate the side effects to intravenous desferrioxamine in a cohort of thalassaemic patients receiving 100 mg/kg/day of desferrioxamine on 3 consecutive days coinciding with blood transfusions on a long term basis.
M P Senanayake
core
Automated Production of [68Ga]Ga-Desferrioxamine B on Two Different Synthesis Platforms
PharmaceuticsBackground/Objectives: PET imaging of bacterial infection could potentially provide added benefits for patient care through non-invasive means. [68Ga]Ga-desferrioxamine B—a radiolabelled siderophore—shows specific uptake by human-pathogenic bacteria like
Martin Kraihammer +7 more
doaj +1 more source
, 2008 It has been suggested that P. falciparum takes up iron from serum and that desferrioxamine, an iron chelating agent, inhibits parasite growth. We have now shown, however, that when all the iron is transferrin bound, P.
T. E. A. Peto, J. L. Thompson
core +1 more source
A Mild and Modular Approach to the Total Synthesis of Desferrioxamine B
A mild and modular approach to the total synthesis of the WHO-listed essential medicine desferrioxamine B is described. Hydroxamic acid fragments were installed under mild conditions, a generalized divergent acylation procedure used to access two monomer
Rachel Codd (1278507) +1 more
core +1 more source