Results 91 to 100 of about 18,392 (257)

In Defense of Desflurane: Is There a Specific Role for Desflurane in Neuroanesthesia?

open access: yesJournal of Neuroanaesthesiology and Critical Care
It is challenging to counter the widespread criticism of desflurane as the volatile anesthetic agent with the most significant greenhouse gas effect, one which is likely to exacerbate global warming.
Shailendra Joshi, Vidur Joshi
doaj   +1 more source

Comparison of maintenance, emergence and recovery characteristics of sevoflurane and desflurane in pediatric ambulatory surgery

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2017
Background and Aims: Increasing number of pediatric ambulatory surgeries are being carried out in general anesthesia using supraglottic airways (SGAs). Literature comparing sevoflurane and desflurane for the maintenance of SGA-based anesthesia is limited.
Manish B Kotwani, Anila D Malde
doaj   +1 more source

Targeting the SIRT1‐NAT10‐GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane‐Induced Cognitive Impairment in Aging

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The study reveals that NAT10 enhances GABABR1 mRNA stability via ac4A modification, leading to excessive inhibitory synaptic activation. In aged rats, sevoflurane contributes to cognitive impairment by inhibiting Sirt1 and neuronal autophagy, which subsequently disrupts energy metabolism.
Xin Xie   +3 more
wiley   +1 more source

Effect of desflurane anesthesia on flash visual evoked potential monitoring in patients undergoing spine surgery: study protocol for a randomized controlled trial

open access: yesTrials
Background Flash visual evoked potentials (FVEPs) are a reliable method for protecting visual function during spine surgery in prone position. However, the popularization and application of FVEPs remain limited due to the unclear influence of various ...
Jiajia Ma   +6 more
doaj   +1 more source

A Systematic Review and Meta‐Analysis of Postoperative Opioid Consumption, Pain and Complications Following Intraoperative Autonomic Nervous System‐Based Nociception Monitoring

open access: yesEuropean Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Autonomic nervous system–based nociception monitors have been proposed to optimise intraoperative opioid administration. While they reduce intraoperative opioid use, evidence on postoperative outcomes remains limited. We conducted a systematic review and meta‐analysis to evaluate their effects on postoperative pain, opioid ...
Mathias A. A. Pietrancosta   +1 more
wiley   +1 more source

Effects of desflurane on central and peripheral clock genes in mice

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the effect and mechanism of the anesthetic drug, desflurane, on central and peripheral clock genes in mice. Methods C57BL/6J mice were anesthetized with different concentrations (3%, 4%, 6%, 7%, 9%) of desflurane, and then the ...
TIAN Hongni   +4 more
doaj   +1 more source

Severe hyperglycaemia associated with prolonged isoflurane anaesthesia in an alpaca (Vicugna pacos)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract Alpacas possess distinct glucose and insulin regulatory mechanisms compared with other species, often maintaining higher baseline blood glucose as a normal physiological adaptation. Inhalant anaesthetic agents can further disrupt glucose, insulin and potassium homeostasis, particularly during prolonged procedures.
Andrea Basler   +3 more
wiley   +1 more source

Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]

open access: yes, 2003
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong   +6 more
core   +1 more source

Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis

open access: yesAnaesthesia, Volume 81, Issue 2, Page 274-287, February 2026.
Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz   +16 more
wiley   +1 more source

Use of MIRUS™ for MAC-driven application of isoflurane, sevoflurane, and desflurane in postoperative ICU patients: a randomized controlled trial

open access: yesAnnals of Intensive Care, 2019
BackgroundThe MIRUS™ (TIM, Koblenz, Germany) is an electronical gas delivery system, which offers an automated MAC (minimal alveolar concentration)-driven application of isoflurane, sevoflurane, or desflurane, and can be used for sedation in the ...
M. Bellgardt   +8 more
semanticscholar   +1 more source

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