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Research progress in the clinical application of inhaled anesthetic sevoflurane. [PDF]
Wu H, Wang S, Dai FB, Tang CL, Tang CL.
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Comparison of the genotoxicity of propofol and desflurane using the comet assay in the lymphocytes of patients who underwent lumbar discectomy: A randomized trial. [PDF]
Toker MK+7 more
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Hepatotoxicity after Desflurane Anesthesia
Anesthesiology, 1995SEVERAL fluorinated inhalation anesthetics have been associated with hepatotoxicity. Yet to date, desflurane has not been reported to cause liver damage in humans. The following is a report of a patient who experienced hepatitis after receiving a desflurane anesthetic and who may have been sensitized by prior halothane exposure.
Michael Charlton+7 more
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Niedrigflußnarkosen mit Desfluran
Der Anaesthesist, 1997Due to its low solubility and negligible metabolism, desflurane is assumed to be especially suitable for application by low-flow anaesthetic techniques. The aim of this clinical investigation was the development of a standardised dosing scheme for low-flow and minimal-flow desflurane anaesthesia.One hundred six ASA status I-II patient were assigned to ...
G Kalff+4 more
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Circulatory Effects of Desflurane
Anaesthesia, 1995SummaryThe cardiovascular properties of desflurane and some other inhalational anaesthetics are outlined and compared, and the way in which they may be effectively used in clinical practice is considered. Desflurane appears to offer some advantages compared with currently available anaesthetics. Its effects on left ventricular function are moderate and
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The Electroencephalographs Effects of Desflurane in Humans
Anesthesiology, 1991The electroencephalographic (EEG) effects of a new inhaled anesthetic are of interest because of the potential of such agents to produce excitatory (convulsant) activity and because of the potential usefulness of the EEG as an indicator of anesthetic depth and cerebral activity.
Nobuhiko Yasuda+5 more
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Cardiopulmonary effects of desflurane in horses
Veterinary Anaesthesia and Analgesia, 2005To determine the cardiopulmonary effects of desflurane (DES) in horses.Six healthy adult horses, three males and three females, aged 9 +/- 4 (mean +/- SD) years and weighing 370 +/- 36 kg.Anaesthesia was induced with an O2 (10 L minute(-1)) and DES mixture (vaporizer setting 18%).
M. Fuente+4 more
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Inhalational anesthetics: Desflurane and sevoflurane
Journal of Clinical Anesthesia, 1995This article reviews the physico-chemical properties and performance characteristics of the two new potent inhaled anesthetics, desflurane and sevoflurane. Both drugs provide a greater degree of control of anesthetic depth and a more rapid immediate recovery from anesthesia than is currently available with other inhaled agents because of their ...
Jeffrey L. Apfelbaum+1 more
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The Influence of Desflurane on QTc Interval
Anesthesia & Analgesia, 2005Volatile anesthetics may prolong the QTc interval and this may result in grave cardiac arrhythmias. We assessed the effect of desflurane on the QTc interval in 40 ASA physical status I or II patients. Volatile anesthetic induction with desflurane was performed, and after obtaining adequate level of anesthesia, QTc interval, heart rate, and noninvasive ...
Radosław Owczuk+4 more
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Depression of Ventilation by Desflurane in Humans
Anesthesiology, 1991We studied the ventilatory effects of desflurane (formerly I-653) with and without N2O in healthy male volunteers. After insertion of venous and arterial (radial and pulmonary) catheters, baseline measurements of tidal volume (VT), respiratory rate (RR), ventilatory response to CO2, and arterial and mixed venous blood gases were made.
Edmond I. Eger+4 more
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