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Hepatotoxicity after Desflurane Anesthesia

Anesthesiology, 1995
SEVERAL fluorinated inhalation anesthetics have been associated with hepatotoxicity. Yet to date, desflurane has not been reported to cause liver damage in humans. The following is a report of a patient who experienced hepatitis after receiving a desflurane anesthetic and who may have been sensitized by prior halothane exposure.
Michael Charlton   +7 more
openaire   +4 more sources

Niedrigflußnarkosen mit Desfluran

Der Anaesthesist, 1997
Due to its low solubility and negligible metabolism, desflurane is assumed to be especially suitable for application by low-flow anaesthetic techniques. The aim of this clinical investigation was the development of a standardised dosing scheme for low-flow and minimal-flow desflurane anaesthesia.One hundred six ASA status I-II patient were assigned to ...
G Kalff   +4 more
openaire   +3 more sources

Circulatory Effects of Desflurane

Anaesthesia, 1995
SummaryThe cardiovascular properties of desflurane and some other inhalational anaesthetics are outlined and compared, and the way in which they may be effectively used in clinical practice is considered. Desflurane appears to offer some advantages compared with currently available anaesthetics. Its effects on left ventricular function are moderate and
openaire   +3 more sources

The Electroencephalographs Effects of Desflurane in Humans

Anesthesiology, 1991
The electroencephalographic (EEG) effects of a new inhaled anesthetic are of interest because of the potential of such agents to produce excitatory (convulsant) activity and because of the potential usefulness of the EEG as an indicator of anesthetic depth and cerebral activity.
Nobuhiko Yasuda   +5 more
openaire   +3 more sources

Cardiopulmonary effects of desflurane in horses

Veterinary Anaesthesia and Analgesia, 2005
To determine the cardiopulmonary effects of desflurane (DES) in horses.Six healthy adult horses, three males and three females, aged 9 +/- 4 (mean +/- SD) years and weighing 370 +/- 36 kg.Anaesthesia was induced with an O2 (10 L minute(-1)) and DES mixture (vaporizer setting 18%).
M. Fuente   +4 more
openaire   +2 more sources

Inhalational anesthetics: Desflurane and sevoflurane

Journal of Clinical Anesthesia, 1995
This article reviews the physico-chemical properties and performance characteristics of the two new potent inhaled anesthetics, desflurane and sevoflurane. Both drugs provide a greater degree of control of anesthetic depth and a more rapid immediate recovery from anesthesia than is currently available with other inhaled agents because of their ...
Jeffrey L. Apfelbaum   +1 more
openaire   +3 more sources

The Influence of Desflurane on QTc Interval

Anesthesia & Analgesia, 2005
Volatile anesthetics may prolong the QTc interval and this may result in grave cardiac arrhythmias. We assessed the effect of desflurane on the QTc interval in 40 ASA physical status I or II patients. Volatile anesthetic induction with desflurane was performed, and after obtaining adequate level of anesthesia, QTc interval, heart rate, and noninvasive ...
Radosław Owczuk   +4 more
openaire   +3 more sources

Depression of Ventilation by Desflurane in Humans

Anesthesiology, 1991
We studied the ventilatory effects of desflurane (formerly I-653) with and without N2O in healthy male volunteers. After insertion of venous and arterial (radial and pulmonary) catheters, baseline measurements of tidal volume (VT), respiratory rate (RR), ventilatory response to CO2, and arterial and mixed venous blood gases were made.
Edmond I. Eger   +4 more
openaire   +3 more sources

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