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Desflurane Clinical Pharmacokinetics and Pharmacodynamics
Clinical Pharmacokinetics, 1994Desflurane is a new volatile anaesthetic agent, with qualitative physiological and pharmacological effects similar to those of previously available drugs of this type. The feature that sets desflurane apart from other halogenated, volatile anaesthetics is its low solubility in blood and body tissues.
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Cardiovascular Actions of Desflurane
1996Desflurane (difluoromethyl-1-fluoro-2,2,2-trifluoroethyl ether; I-653), a structural analog of isoflurane, possesses remarkable metabolic stability. It has very low blood- and tissue-gas partition coefficients which facilitates rapid anesthetic induction, alterations in anesthetic depth, and emergence in a variety of clinical settings.
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Physicochemical properties and pharmacodynamics of desflurane
Anaesthesia, 1995SummaryDesflurane is a new volatile, inhaled anaesthetic that differs significantly from presently available inhaled agents in being halogenated solely with fluorine. This fluorination produces a lower solubility and increased resistance to biodegradation.
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Discolored Desflurane in the Vaporizer
Anesthesia & Analgesia, 2010Thomas E. Schulte, Sheila J. Ellis
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Desflurane Is Not an Isomer of Isoflurane
Anesthesiology, 1994Harold Arkoff +2 more
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Desflurane, Isoflurane, and…Ragweed
Anesthesiology, 2013Carl Lynch, Mohamed Tiouririne
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Sevoflurane and Desflurane Confusion
Anesthesia & Analgesia, 1999Serge M. Broka +2 more
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