Results 271 to 280 of about 18,570 (301)

The Influence of Desflurane on QTc Interval

Anesthesia & Analgesia, 2005
Volatile anesthetics may prolong the QTc interval and this may result in grave cardiac arrhythmias. We assessed the effect of desflurane on the QTc interval in 40 ASA physical status I or II patients. Volatile anesthetic induction with desflurane was performed, and after obtaining adequate level of anesthesia, QTc interval, heart rate, and noninvasive ...
Radosław Owczuk, Jerzy Lasek, Maria Wujtewicz, Magdalena A. Wujtewicz, Wioletta Sawicka   +4 more
openaire   +3 more sources

Depression of Ventilation by Desflurane in Humans

Anesthesiology, 1991
We studied the ventilatory effects of desflurane (formerly I-653) with and without N2O in healthy male volunteers. After insertion of venous and arterial (radial and pulmonary) catheters, baseline measurements of tidal volume (VT), respiratory rate (RR), ventilatory response to CO2, and arterial and mixed venous blood gases were made.
Edmond I. Eger, Ira J. Rampil, Richard B. Welskopf, Stephen H. Lockhart, Nobuhiko Yasuda   +4 more
openaire   +3 more sources

Reduction of the MAC of Desflurane with Fentanyl

Anesthesiology, 1992
Opioids are known to affect the MAC of inhalational anesthetics. We have determined the interaction between fentanyl and desflurane, following a bolus injection of fentanyl at induction in 134 adult patients. Five groups of patients were studied. Four groups received desflurane or isoflurane in oxygen with either fentanyl 3 or 6 micrograms/kg and ...
Christopher J. Gallagher, Peter S. A. Glass, T J Quill, Peter S. Sebel, Michael R. Murphy, J.E. Fletcher   +5 more
openaire   +3 more sources

Sympathetic Activation with Desflurane in Humans

1994
Although the blood pressure lowering effects of desflurane and isoflurane were similar at equi-MAC, we noted a different pattern of response during intervals of rapidly increasing the inspired concentration of desflurane, when substantial increases in SNA, HR, and MAP occurred.
Michael Muzi, Thomas J. Ebert
openaire   +3 more sources

Desflurane and Density

Anesthesiology, 2007
Dimitris Georgopoulos, Helen Askitopoulou, George Prinianakis, Vasilia G. Nyktari, Alexandra A. Papaioannou   +4 more
openaire   +5 more sources

Propofol Attenuates the Myocardial Protection Properties of Desflurane by Modulating Mitochondrial Permeability Transition

Anesthesia and Analgesia, 2018
BACKGROUND: Desflurane and propofol are cardioprotective, but relative efficacy is unclear. The aim was to compare myocardial protection of single, simultaneous, and serial administration of desflurane and propofol.
J. Heiberg, C. Royse, A. Royse, D. T. Andrews   +3 more
semanticscholar   +1 more source

Effects of Desflurane in Senescent Rat Myocardium

Anesthesiology, 2006
Background The myocardial negative inotropic effects of desflurane are less pronounced than those of other halogenated anesthetics, partly because of intramyocardial catecholamine store release. However, the effects of desflurane on aging myocardium are unknown, whereas aging is known to be associated with an attenuation of ...
Rozenberg, S., Besse, S., Amour, J., Viven, B., Tavernier, B., Riou, B.   +5 more
openaire   +4 more sources

Cardiovascular Actions of Desflurane

1996
Desflurane (difluoromethyl-1-fluoro-2,2,2-trifluoroethyl ether; I-653), a structural analog of isoflurane, possesses remarkable metabolic stability. It has very low blood- and tissue-gas partition coefficients which facilitates rapid anesthetic induction, alterations in anesthetic depth, and emergence in a variety of clinical settings.
openaire   +2 more sources

Desflurane Clinical Pharmacokinetics and Pharmacodynamics

Clinical Pharmacokinetics, 1994
Desflurane is a new volatile anaesthetic agent, with qualitative physiological and pharmacological effects similar to those of previously available drugs of this type. The feature that sets desflurane apart from other halogenated, volatile anaesthetics is its low solubility in blood and body tissues.
openaire   +3 more sources

Comparison of the Conox (qCON) and Sedline (PSI) depth of anaesthesia indices to predict the hypnotic effect during desflurane general anaesthesia with ketamine

Journal of clinical monitoring and computing, 2020
C. Christenson, Pablo Martinez-Vazquez, Max W. Breidenstein, Borzoo Farhang, J. Mathews, U. Melia, E. Jensen, Donald Mathews   +7 more
semanticscholar   +1 more source