Results 81 to 90 of about 30,982 (310)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Experimental study of a membrane-based dehumidification cooling system [PDF]

open access: yes, 2016
Membrane-based liquid desiccant dehumidification has attracted increasing interests with elimination of solution droplets carryover problem. A membrane-based hybrid liquid desiccant dehumidification cooling system is developed in this study, which has ...
Bai, Hongyu   +3 more
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Functional packaging materials : factors affecting the capacity and rate of water adsorption in desiccant composites [PDF]

open access: yes, 2013
Ten different polymers were selected as possible matrix for zeolite containing desiccant composites in order to prepare functional packaging material. Water uptake was de-termined at 100 % RH and the results were analyzed to identify factors influencing ...
Kajtár, Dóra Andrea   +4 more
core   +1 more source

Aplicação tardia de glyphosate e estande e desenvolvimento inicial do arroz em sistema de cultivo mínimo Delayed application of glyphosate and stand and initial growth of rice plants (Oryza sativa) under a minimum tillage system

open access: yesPlanta Daninha, 2002
O controle de plantas daninhas na cultura do arroz é ainda um problema, mesmo em cultivo mínimo, em razão do revolvimento do solo na linha de semeadura, que proporciona o reaparecimento de infestantes.
C.A.C. Crusciol   +3 more
doaj   +1 more source

Energy Efficiency in Greenhouse Evaporative Cooling Techniques: Cooling Boxes versus Cellulose Pads [PDF]

open access: yes, 2014
Evaporative cooling systems using a combination of evaporative pads and extractor fans require greenhouses to be hermetic. The greatest concentration of greenhouses in the world is located in southeast Spain, but these tend not to be hermetic structures ...
Franco Salas, Antonio   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Polyamide Nanocomposites for Selective Laser Sintering [PDF]

open access: yes, 2006
Current polyamide 11 and 12 are lacking in fire retardancy and high strength/high heat resistance characteristics for a plethora of finished parts that are desired and required for performance driven applications.
Cheng, J.   +6 more
core   +1 more source

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