Results 41 to 50 of about 56,912 (284)
Frontiers in Physiology, 2020 Water is critical for the survival of most cells and organisms. Remarkably, a small number of multicellular animals are able to survive nearly complete drying.
Jonathan D. Hibshman +3 more
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FEBS Open Bio, 2020 The tardigrade Hypsibius exemplaris can undergo anhydrobiosis. Several chemicals that inhibit successful anhydrobiosis in H. exemplaris have been identified, and these chemicals inhibit the activity of signaling molecules.
Koyuki Kondo +3 more
doaj +1 more source
LEA polypeptide profiling of recalcitrant and orthodox legume seeds reveals ABI3-regulated LEA protein abundance linked to desiccation tolerance [PDF]
, 2013 In contrast to orthodox seeds that acquire desiccation tolerance during maturation, recalcitrant seeds are unable to survive drying. These desiccation-sensitive seeds constitute an interesting model for comparative analysis with phylogenetically close ...
H. Rogniaux +5 more
core +5 more sources
Desiccation tolerance of prokaryotes
Microbiological Reviews, 1994 The removal of cell-bound water through air drying and the addition of water to air-dried cells are forces that have played a pivotal role in the evolution of the prokaryotes. In bacterial cells that have been subjected to air drying, the evaporation of free cytoplasmic water (Vf) can be instantaneous, and an equilibrium between cell-bound water (Vb ...
openaire +2 more sources
BMC Zoology, 2021 Background Increasing temperatures and changes in precipitation patterns threaten the existence of many organisms. It is therefore informative to identify the functional traits that underlie differences in desiccation resistance to understand the ...
Beatrice Nervo +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
mBio, 2011 Streptococcus pneumoniae (pneumococcus) is a frequent colonizer of the nasopharynx and one of the leading causative agents of otitis media, pneumonia, and meningitis. The current literature asserts that S.
Rebecca L. Walsh, Andrew Camilli
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Desiccation tolerance of eggplant pollen [PDF]
, 2010 A alta demanda por sementes híbridas tem estimulado pesquisas que asseguram a oferta destas, como é o caso da manipulação de grãos de pólen. Assim, em estudo conduzido na Embrapa Hortaliças, no ano de 2006, objetivou-se determinar a tolerância à ...
Carmona, Ricardo +3 more
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Understanding desiccation tolerance using the resurrection plant Boea hygrometrica as a model system
Frontiers in Plant Science, 2013 Vegetative tissues of Boea hygrometrica, a member of the Gesneriaceae family, can tolerate severe water loss to desiccated state and fully recover upon rehydration. Unlike many other so called resurrection plants, the detached leaves of B.
Jayeeta eMitra +5 more
doaj +1 more source