Results 61 to 70 of about 104,722 (311)

Modeling of Multi-Cell HBT Device Based on Device Structure

Micromachines
This paper focuses on the modeling challenges of a multi-cell heterojunction bipolar transistor (HBT) used in radio frequency (RF) power amplifiers and proposes an innovative linear small-signal modeling method. Based on devices with an emitter size of 3
Haoyi Zhao, Jun Liu, Tao Rong, Shiyue Fan, Zhanfei Chen, Junchao Wang   +5 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Applications of evolutionary algorithms in the design automation of analog integrated circuits [PDF]

, 2010
During the last decade, evolutionary algorithms (EAs) have shown its usefulness for solving multi-objective optimization problems. In the field of analog Integrated Circuits (ICs), they provide a set of feasible solutions for the optimal synthesis and ...
MIGUEL AURELIO DUARTE VILLASEÑOR, IVICK GUERRA GOMEZ, LUIS GERARDO DE LA FRAGA, ESTEBAN TLELO CUAUTLE, GERARDO REYES SALGADO, GUSTAVO RODRIGUEZ GOMEZ, CARLOS ALBERTO REYES GARCIA, GEORGINA FLORES BECERRA   +7 more
core  

An Improved Parameter Extraction Optimization Algorithm for RF Devices

Micromachines
This paper proposes an improved parameter extraction optimization algorithm for radio frequency (RF) devices. The algorithm integrates parameter classification and correction, gradient-based performance handling, bias-aware updates, and group-based ...
Shengsen Yang, Zihan Xu, Kun Ren
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Design automation for IEEE P1687

, 2011
The IEEE P1687 (IJTAG) standard proposal aimsat standardizing the access to embedded test and debug logic(instruments) via the JTAG TAP. P1687 specifies a componentcalled Segment Insertion Bit (SIB) which makes it possible toconstruct a multitude of ...
E Larsson, Larsson, Erik,, F G Zadegan, G Carlsson, Zadegan, Farrokh Ghani,, Ingelsson, Urban,, U Ingelsson, Carlsson, Gunnar,   +7 more
core   +1 more source

Design of a Hybrid Asymmetric LMBA With High Linearity Based on Improved Particle Swarm Optimization Method

IEEE Open Journal of Circuits and Systems
This paper presents an improved particle swarm optimization (PSO) method and applies it to the design of a hybrid asymmetric load modulated balanced amplifier (H-ALMBA) with high linearity. A description is provided of the H-ALMBA topology as well as the
Benhao Jin, Zhiming Fan, Giovanni Crupi, Jialin Cai   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Design automation based on fluid dynamics [PDF]

, 2017
This article was accepted and presented at the 9th International Workshop on Bio-Design Automation, Pittsburgh, Pennsylvania (2017).Microfluidic devices provide researchers with numerous advantages such as high throughput, increased sensitivity and ...
Densmore, Douglas, Lippai, Joshua, Sanka, Radhakrishna, Lashkaripour, Ali   +3 more
core  

Embedded system design

, 2022
S.5-50In the past decade the main engine of electronic design automation has been the widespread application of ASICs (Application Specific Integrated Circuits).
Camposano, R., Wilberg, J.
core   +1 more source