Results 91 to 100 of about 4,753,099 (348)

The natural flow wing-design concept [PDF]

open access: yes
A wing-design study was conducted on a 65 degree swept leading-edge delta wing in which the wing geometry was modified to take advantage of the naturally occurring flow that forms over a slender wing in a supersonic flow field.
Bauer, Steven X. S., Wood, Richard M.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Design concept for nonarcing electrical connector [PDF]

open access: yes, 1968
Connector plug automatically minimizes arcing during mating and demating. This plug uses a high-resistivity outer sheath as an extension to the regular pin contact.
Holmen, R. E.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Active concept in pedestrian design

open access: yesARTEKS : Jurnal Teknik Arsitektur, 2017
Saat ini terdapat tren perancangan kota dengan konsep active living yang membuat penduduk kota menjadi lebih aktif bergerak, secara keseluruhan menjadikan kota lebih sehat (healthy city).
Christianto Hendrawan   +1 more
doaj   +1 more source

The Revitalization Concept of “Pramuka Penggalang” in The Digital Game Design [PDF]

open access: yes, 2019
The scout activity is a non-formal education in environments such as school and family. Generally, it held in the outdoors as an attractive place, challenging, creative, innovative, and fun.
Budiman, A. (Arief)   +1 more
core  

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