Results 91 to 100 of about 4,347,183 (334)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 1979-1997, July 2025.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 1897-1917, July 2025.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Active concept in pedestrian design

open access: yesARTEKS : Jurnal Teknik Arsitektur, 2017
Saat ini terdapat tren perancangan kota dengan konsep active living yang membuat penduduk kota menjadi lebih aktif bergerak, secara keseluruhan menjadikan kota lebih sehat (healthy city).
Christianto Hendrawan   +1 more
doaj   +1 more source

The application of multi-objective robust design methods in ship design [PDF]

open access: yes, 1999
When designing large complex vessels, the evaluation of a particular design can be both complicated and time consuming. Designers often resort to the use of concept design models enabling both a reduction in complexity and time for evaluation.
Coates, Graham   +2 more
core  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 1935-1967, July 2025.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

The natural flow wing-design concept [PDF]

open access: yes
A wing-design study was conducted on a 65 degree swept leading-edge delta wing in which the wing geometry was modified to take advantage of the naturally occurring flow that forms over a slender wing in a supersonic flow field.
Bauer, Steven X. S., Wood, Richard M.
core   +1 more source

A novel design concept for space-based polar remote sensing [PDF]

open access: yes, 2012
Space-based remote sensing of the Earth is conducted from a fleet of spacecraft in two basic orbital positions, near-polar low-Earth orbits and geosynchronous orbits, with each offering its own advantages and disadvantages.
Anderson, Pamela   +2 more
core  

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