Results 111 to 120 of about 4,803,101 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An hierarchical approach to hull form design [PDF]
, 2003 As ship design tools become more integrated and more advanced analysis tools are introduced, the ability to rapidly develop and modify hull forms becomes essential. Modern hull design applications give an experienced user the ability to create almost any
Bole, M., Lee, B.S.
core
A novel integrated MADM method for design concept evaluation. [PDF]
Sci Rep, 2022 Chen Z, Zhong P, Liu M, Ma Q, Si G.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
An MAGDM method for design concept evaluation based on incomplete information. [PDF]
PLoS One, 2022 Chen Z, Pan Z, Ma Q, Hou T, Zhao P.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
From sign to design: The role of domain transfer in redefining architecture locality
ARTEKS : Jurnal Teknik ArsitekturThis research examines the design process using conceptual frameworks based on domain transfer to suggest a new model for architecture based on local contexts.
Bramasta Putra Redyantanu +1 more
doaj +1 more source
Rotorcraft flight-propulsion control integration: An eclectic design concept [PDF]
The NASA Ames and Lewis Research Centers, in conjunction with the Army Research and Technology Laboratories, have initiated and partially completed a joint research program focused on improving the performance, maneuverability, and operating ...
Ballin, Mark G. +2 more
core +1 more source
Heinz Isler: shells for two churches [PDF]
, 2011 This paper describes the concept, design and realisation of two churches where Heinz Isler (1926-2009) was responsible for the structural design and in one case also for the architectural concept. One example, the Heilig Geist Kirche (Holy Spirit Church)
Chilton, JC
core
A design concept of big data analytics model for managers in hospitality industries. [PDF]
Pers Ubiquitous Comput, 2023 Mousavian S, Miah SJ, Zhong Y.
europepmc +1 more source