Results 121 to 130 of about 4,803,101 (299)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Creative vs Defective: A Critical Review of Malang Creative Center (MCC) in Malang City

open access: yesRUAS
The Malang Creative Center (MCC) construction is a step taken by the Malang City government to support the flow of modernization and as a forum for Malang residents to develop their creativity. The MCC display concept is planned by combining the shape of
Bunga Pasadena Ineru   +4 more
doaj   +1 more source

Human centred manufacturing: methodology for ergonomic previsional evaluation of manual assembly operations [PDF]

open access: yes, 2013
The challenge of flexibility and productivity for manufacturing operations needs a new concept based on “human-centered manufacturing process”. This concept must consider basically the ergonomics of workplaces and workload balancing.
Costantino, Marco   +3 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Design as a Literary Concept? [PDF]

open access: yesSlovenska Literatura, 2014
In relation to his book Černá kočka aneb Subjekt znalce v myšlení o literatuře a jeho komunikační strategie (A Black Cat or The Subject of the Expert in Literary Thinking and His Communication Strategies, Praha, Academia 2012), the writer of the article ...
Pavel Janoušek
doaj  

Comics, robots, fashion and programming: outlining the concept of actDresses [PDF]

open access: yes, 2009
This paper concerns the design of physical languages for controlling and programming robotic consumer products. For this purpose we explore basic theories of semiotics represented in the two separate fields of comics and fashion, and how these could be ...
Fernaeus, Ylva, Jacobsson, Mattias
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Changing Human Factor in the Concept of Design and Changing Inclusive Design Approaches

open access: yesIDA: International Design and Art Journal, 2020
The starting point of the design concept is considered concurrent with the history of humanity. In designing, which directly depends on humans with its existence, all the products, both abstract and concrete, are addressed to meet the needs of human ...
Zeynep ACIRLI, Özge KANDEMİR
doaj  

Caging Mechanism for a drag-free satellite position sensor [PDF]

open access: yes, 1976
A disturbance compensation system for satellites based on the drag-free concept was mechanized and flown, using a spherical proof mass and a cam-guided caging mechanism.
Debra, D. B., Hacker, R., Mathiesen, J.
core   +1 more source

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