Results 91 to 100 of about 1,419,472 (305)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

What’s D&T for? Gathering and comparing the values of design and technology academics and trainee teachers

open access: yes, 2015
Some who read and research about Design & Technology (D&T) would say that the concept of value is key to understanding and defining D&T. Closer inspection reveals though that there are two ways in which values are defined in D&T: how values are taught ...
Hardy, Alison, Hardy, A
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Combining Axiomatic Design and Case-Based Reasoning in a Design Methodology of Mechatronics Products [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityCurrent market environments are volatile and unpredictable. The ability for design products to meet customer’s requirements has become critical to success.
Janthong, N.   +5 more
core  

Active concept in pedestrian design

open access: yesARTEKS : Jurnal Teknik Arsitektur, 2017
Saat ini terdapat tren perancangan kota dengan konsep active living yang membuat penduduk kota menjadi lebih aktif bergerak, secara keseluruhan menjadikan kota lebih sehat (healthy city).
Christianto Hendrawan   +1 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Concept exploration on the design requirements and design scheme of laser shock processing equipment [PDF]

open access: yes, 2013
In order to development the laser shock processing equipment, the technical features and process demand are analysis. The design requirements about laser shock processing equipment are discussed in detail by the methods of use case analysis and sequence ...
Deng HB(邓华波)   +2 more
core  

Design concept for bolted Glass

open access: yesChallenging Glass Conference Proceedings, 2010
For the design of load carrying glazing structures the connection technique plays an important role, as e.g. there are significant stress concentrations in the vicinity of holes that are subject to a point-like support of glass panes.
M. Baitinger, M. Feldmann
doaj   +1 more source

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