Results 161 to 170 of about 4,803,101 (299)
Confusing concepts in study design
Anupam Das, Aparajita Ghosh
openaire +3 more sources
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Konsep Penataan Lingkungan Koridor Berbatas Pagar Perumahan Skala Besar
Kondisi koridor selatan Kejawan Putih Tambak Surabaya terkait posisinya yang berbatas pagar perumahan skala besar membuat koridor ini memiliki berbagai masalah akibat keberadaan pagar pembatas itu sendiri. Berbagai dampak akibat tidak jelasnya kewenangan
Fibria Conytin Nugrahini, Rofi'i Rofi'i
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Intelligent Face Recognition System Based on Universal Design Concept.
Li Z, Shin K.
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Application of the Safe-By-Design Concept in Crop Breeding Innovation. [PDF]
van der Berg JP +4 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Application of formal optimization techniques in thermal/structural design of a heat-pipe-cooled panel for a hypersonic vehicle [PDF]
Nonlinear mathematical programming methods are used to design a radiantly cooled and heat-pipe-cooled panel for a Mach 6.7 transport. The cooled portion of the panel is a hybrid heat-pipe/actively cooled design which uses heat pipes to transport the ...
Camarda, Charles J., Riley, Michael F.
core +1 more source

