Results 81 to 90 of about 4,753,099 (348)

Design and proof of concept for silicon-based quantum dot quantum bits [PDF]

open access: yes, 2002
Spins based in silicon provide one of the most promising architectures for quantum computing. Quantum dots are an inherently scalable technology. Here, we combine these two concepts into a workable design for a silicon-germanium quantum bit.
Eriksson, Mark A.   +6 more
core   +2 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Aplikasi Nilai Objektivitas pada Konsep Desain Interior Kantor

open access: yesHumaniora, 2013
Now days, planning an office was more than preparing desk and chair, it needed  numbers of important decisions to be considerered, such as, where and how did the workers want to work?, What kinds of workspace that supported  employee’s activities and how
Ulli Aulia Ruki
doaj   +1 more source

Criticism and Function in Critical Design Practice [PDF]

open access: yes, 2015
This article focuses on critical design as a field of industrial design practice. It considers some barriers and misconceptions to critical design practice being seen as part of a disciplinary project.
Malpass, Matt
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Concept models for design practice

open access: yesBitácora Urbano Territorial, 2017
Concept models are common guides to living, and some more specialized ones, which have been developed and validated in other fields have been adopted by designers for use in their work. In particular, concept models serve as templates for decision-making
Stan Ruecker
doaj   +1 more source

Computer-aided design of large-scale integrated circuits - A concept [PDF]

open access: yes, 1971
Circuit design and mask development sequence are improved by using general purpose computer with interactive graphics capability establishing efficient two way communications link between design engineer and system. Interactive graphics capability places
Schansman, T. T.
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Mechanical properties and impact resistance mechanism of anchor bolts under dynamic-static coupling conditions

open access: yesMeitan xuebao
Anchor bolt support is a commonly used surrounding rock control technology in deep underground engineering. To control the large deformation of surrounding rock under complex conditions, high prestress needs to be applied to the anchor bolts.
Qi WANG   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy