Results 111 to 120 of about 1,258,449 (312)

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

The h-Index of Editorial Board Members Correlates Positively With the Impact Factor of Sports Medicine Journals

open access: yesOrthopaedic Journal of Sports Medicine, 2017
Background: The h-index is a metric widely used to present both the productivity and impact of an author’s previous publications. Purpose: To evaluate and observe any correlations among the h-indices of 2015 editorial board members from 8 top sports ...
Jeffrey Kay BSc   +6 more
doaj   +1 more source

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Housing Norms and Standards: The Design of Everyday Life

open access: yesUrban Planning
This editorial introduces the articles in this thematic issue, which bridge the gap between technical housing standards, design practices, and socio-cultural norms.
Sam Jacoby, Seyithan Özer
doaj   +1 more source

Design Editorial Algorítmico

open access: yes, 2019
Dissertação de Mestrado em Design e Multimédia apresentada à Faculdade de Ciências e ...
openaire   +1 more source

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

open access: yesAdvanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman   +3 more
wiley   +1 more source

O projeto gráfico de periódicos científicos: uma contribuição aos roteiros de avaliação

open access: yesEm Questão, 2005
O presente artigo estuda a relação entre projetos gráfico e editorial de periódicos na comunicação científica. Para isso, apresenta e discute os modos como estes veículos vêm sendo avaliados, bem como as peculiaridades do processo de design editorial e ...
Raquel da Silva Castedo   +1 more
doaj  

ANALISIS KOHESI GRAMATIKAL DAN LEKSIKAL PADA TAJUK RENCANA HARIAN THE JAKARTA POST [PDF]

open access: yes, 2011
Zaharil.Anasy.A4C106001. 2011. Analisis Kohesi Gramatikal dan Kohesi Leksika pada Tajuk Rencana Harian The Jakarta Post. Tesis. Program Pasca Sarjana Universitas Diponegero Semarang. Penelitian ini adalah penelitian pada bidang wacana.
Anasy, Zaharil
core  

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang   +17 more
wiley   +1 more source

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