Results 131 to 140 of about 5,666,479 (292)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Integrating Architectural Approaches in Communication Design Education to Improve Awareness in Affordance Design [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2017
The expansion of the range for the design of products in the field of Communication Design (CoD) calls for new teaching strategies to be sought by educational scholars due to the intense experience of digital natives with the digital tools and technology.
Simge Esin Orhun
doaj  

INNOWIZ: a guided framework for projects in industrial design education [PDF]

open access: yes, 2012
This paper presents the concrete application of the INNOWIZ methodology in a design education context. This methodical philosophy is used as a structural backbone in teaching the product design process to students in industrial product design ...
Michiels, Pieter   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Editorial: Teaching and learning human–computer interaction (HCI): current and emerging practices

open access: yesFrontiers in Computer Science, 2023
Craig M. MacDonald   +7 more
doaj   +1 more source

Levels of expertise in design education [PDF]

open access: yes, 2004
Design ability and differences between novice and expert designers have been quite extensively studied in the field of design methodology. For example, design expertise got much attention in the latest Design Thinking Research Symposium held in Australia.
Dorst, Kees, Reymen, Isabelle
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Innovative collaborative design in international interaction design summer schools [PDF]

open access: yes, 2009
[About the book]: Design is changing, and to educate the next generation of designers, these changes need to be addressed. In light of the growing role research and interdisciplinary collaboration play in contemporary design performance, Design ...
Schadewitz, Nicole
core  

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