Results 81 to 90 of about 5,644,068 (291)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Re-imaging the Environment [PDF]
, 2013 This paper represents a study of selected visualisation and investigative methods that facilitate the exploration and expression of human emotions and perceptions within real world environments during the design development stages of a project ...
Mace, Valerie
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Components of the "Crit" in Art and Design Education
Irish Journal of Academic Practice, 2016 The design jury, design critique, or crit is a common teaching and learning strategy within art and design, and architecture education. The crit dates from the nineteenth century Beaux-Arts school of architecture education and has since evolved into a ...
John Healy
doaj +1 more source
The Effect Of Adobe Flash Based Educating Game On Cognitive Capability Of Early Age Children In Tk Aisyiyah I Gumpang [PDF]
, 2013 This research was intended to study whether Adobe Flash based education game can improve cognitive capability of early age children in TK Aisyiyah I Gumpang class B, particularly in simple number recognition subject.
Aulia, Irfani
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Cubic Journal, 2023 Failures in achieving sustainability are being recognised worldwide. Approaches to tackling sustainability challenges often fail to address the roots of these challenges.
Mariana Fonseca Braga
doaj
The influence of national policies on the evolution of industrial design education in China. [PDF]
Heliyon, 2023 Li S, Zhang Y, Wang Z, Li H.
europepmc +1 more source
Helping design educators foster collaborative learning amongst design students [PDF]
, 2010 This paper discusses the development of online teaching resources that enable design educators to foster collaborative learning amongst students in the design disciplines.
Jefferies, Emma +2 more
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source