Results 71 to 80 of about 80,005 (169)

When matter leads to form: Material driven design for sustainability

Temes de Disseny, 2018
This article presents the argument that a conventional, form-focused design process causes a lack of knowledge regarding materials and, as a result, creates a knowledge barrier between the designer and the product – a barrier that acts not only against ...
Mette Bak-Andersen
doaj  

ARTIFICIAL INTELLIGENCE IN THE FORMATION OF CULTURAL COMPETENCE OF FUTURE DESIGNERS: THE DIDACTIC ASPECT OF THE CREATIVE ECONOMY

Economics & Education
The subject of this study is the didactic potential of artificial intelligence in the formation of cultural competence among future designers in the context of the creative economy.
Tetiana Zubko, Marianna Adamovska
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Evaluating the Effectiveness of VR in Architectural Design Education: A Comparison Across Student Levels Using Pointing Out Mistakes in Design Plans

Buildings
Background: Virtual reality (VR) has attracted increasing attention in architectural design education because of its potential to support spatial cognition and embodied understanding of architectural space. Compared with conventional two-dimensional (2D)
Ning Hou, Daisaku Nishina, Sayaka Kindaichi, So Sugita, Shunki Nishii   +4 more
doaj   +1 more source

Almost Risking It All

Cubic Journal, 2021
This paper provides an argument against understanding risk-taking in design education as something ideally in need of only being calculable and formalisable.
Bo Allesøe Christensen, Peter Vistisen, Thessa Jensen   +2 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Quantifying the Fluency Illusion in AI-Augmented Design Education: A Behavioral Soft-Sensor Framework for Decoding Human–AI Collaboration Patterns

Applied System Innovation
Generative artificial intelligence (GenAI) has transformed design education, yet growing evidence suggests that the fluency of AI-generated outputs may create a “fluency illusion”—a metacognitive bias whereby learners conflate polished AI artifacts with ...
Yanfei Tang, Wai Yie Leong
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Developing a student-perceived satisfaction scale for design studio teaching in Chinese universities

Frontiers in Education
The studio teaching model, originating from the Bauhaus in Germany, has played a central role in design education; however, a systematic framework for evaluating its effectiveness remains underdeveloped. This study aimed to develop and validate a student-
Yu-Tong Chen, Guo-Qing Pan, Jeng-Chung Woo, Jeng-Chung Woo, Feng Luo, Zhe-Hui Lin, Yu-Wei Lin   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source