Results 71 to 80 of about 4,260,477 (269)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The influence of product design on establishing brand equity
, 2008 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This study investigated the role of product design on brand equity by investigating the effect of consumers' perception about product design on brand equity.
Na, Kwang Jin
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Where product design meets investor behavior : how do individual investors' evaluations of companies' product design influence their investment decisions? [PDF]
, 2009 Design management research has increasingly advocated strategic perspectives to product design. However, one important, strategic business aspect has been rather completely ignored in extant research.
Aspara, Jaakko
core
Design of indomethacin-loaded nanoparticles: effect of polymer matrix and surfactant
International Journal of Nanomedicine, 2013 Danay Dupeyrón,1,2 Monique Kawakami,1 Adriana M Ferreira,1 Paolin Rocio Cáceres-Vélez,3 Jacques Rieumont,4 Ricardo Bentes Azevedo,3 José Carlos T Carvalho1 1Laboratório de Pesquisa em Fármacos, Centro de Ciê
Dupeyrón D +6 more
doaj
Tunnel design considering stress release effect
Water Science and Engineering, 2009 In tunnel design, the determination of installation time and the stiffness of supporting structures is very important to the tunnel stability. This study used the convergence-confinement method to determine the stress and displacement of the tunnel while
Van-hung Dao
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Experimental PhysiologyThe design of in vivo studies using laboratory animals is normally guided by the 3Rs: Replacement, Reduction and Refinement. The concept of Reduction is particularly important in the context of estimating sample size; the selected sample size should ...
Crispin Jordan +2 more
doaj +1 more source
Some useful ideas for multistate protein design: Effect of amino acid substitutions on the multistate proteins stability and the rate of protein structure formation. [PDF]
Front Mol Biosci, 2022 Majorina MA +3 more
europepmc +1 more source