Results 81 to 90 of about 4,260,477 (269)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design Effect in Multilevel Settings: A Commentary on a Latent Variable Modeling Procedure for Its Evaluation. [PDF]
Educ Psychol Meas, 2022 Raykov T, DiStefano C.
europepmc +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Design with benefits: hearth fire nights and bittersweet chores
, 2016 This paper presents \u27designs with benefits\u27 by capitalising on the joint benefits of sustainability and wellbeing. Designs with benefits are proposed through four ‘in-between’ themes for design goals as a new direction in supporting sustainability ...
Stella U. Boess +3 more
core +1 more source
Journal of Engineering, 2016 The natural ventilation in buildings is one of effective strategies for achieving energy efficiency in buildings by employing methods and ways of passive design, as well as its efficiency in providing high ranges of thermal comfort for occupants in ...
Ghada M.Ismael Abdul Razzaq Kamoona, Dr
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Value-driven simulation : thinking together through simulation in early engineering design
, 2017 The topic of ‘design for value’ has lately attracted a great deal of attention within the engineering design community. ‘Predicting’ the value of a future solution is however difficult, especially in early design phases.
Jonsson, Pontus +9 more
core
The Effect of microstructural heterogeneities on the fatigue behaviour of 22MnB5 sheet steel [PDF]
, 2013 This work deals with the effect of heat treatment on the fatigue strength of a rear axial beam and aims to propose a methodology suitable and reliable for fatigue design.
PESSARD, Etienne +4 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source