Results 51 to 60 of about 4,605,170 (283)

A framework for design engineering education in a global context [PDF]

, 2010
This paper presents a framework for teaching design engineering in a global context using innovative technologies to enable distributed teams to work together effectively across international and cultural boundaries.
Ade Mabogunje, Andrew J. Wodehouse, Bates, Caroline Breslin, Eris, Grierson, Hilary J. Grierson, Larry J. Leifer, Love, Mills, Ozgur Eris, Prosser, Twigg, William J. Ion   +13 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Effect of design and kinematic parameters on energy requirement in inclined screw mixer

Advanced Engineering Research, 2018
Introduction. Rational parameters and modes of an inclined batch screw mixer are validated to achieve the lowest energyintensive feed mixing under observance of the zootechnical requirements for the feed quality on uneven mixing.
V. F. Khlystunov, S. V. Braginets, A. S. Alferov, M. V. Chernutskiy   +3 more
doaj   +1 more source

Approaches to the teaching of design : an engineering subject centre guide [PDF]

, 2009
This booklet seeks to provide a resource for all those with an interest in design, and the education and training of engineering students to carry out the design process.
Mclaren, Andrew
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

TECHNOLOGY OF ART AND DESIGN ANALYSIS ON THE CASE STUDY MALE DAGHESTAN NATIONAL COSTUME

Вестник Дагестанского государственного технического университета: Технические науки, 2016
The article considers the stages of artistic analysis of masculine humeral service widespread on the territory of Daghestan in the nineteenth and early twentieth centuries. For example Circassian presents illustrative material: photos, technical drawing,
T. M. Serova
doaj   +1 more source

Ethics – research, engineering, design… they’re all the same aren’t they? [PDF]

, 2014
This paper considers how and to what extent product design ethics is understood by professionals in design practice and undergraduate students of product and engineering design and how, if at all, design ethics differ from engineering and/or research ...
Blount, G., Humphries-Smith, Tania, Powell, J.   +2 more
core  

Introducing systems engineering to industrial design engineering students with hands-on experience [PDF]

, 2005
The article presents an innovative educational project to introduce systems engineering to third year students in industrial design engineering at the University of Twente. In a short period the students are confronted with new technology, namely sensors
Bonnema, G. Maarten, Houten, Fred J.A.M. van, Lutters-Weustink, Ilanit F.   +2 more
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Building a Common Ground – The Use of Design Representation Cards for Enhancing Collaboration between Industrial Designers and Engineering Designers [PDF]

, 2009
To achieve success in today’s commercial environment, manufacturers have progressively adopted collaboration strategies. Industrial design has been increasingly used with engineering design to enhance competitiveness.
Campbell, Ian, Evans, Mark A, Pei, Eujin
core