Results 71 to 80 of about 1,013,397 (268)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Influence of liquid film thickness on bearing characteristics of magnetic-liquid suspension guide-way

open access: yesThe Journal of Engineering, 2018
The magnetic-liquid suspension guide-way (MLSG) adopts the double support form of permanent magnetic suspension and hydrostatic pressure. It can greatly enhance the bearing capacity and rigidity of the guide-way system.
Jianhua Zhao   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Analysis and experimental validation of a pressure control method using magneto-rheology fluid flows

open access: yesThe Journal of Engineering, 2018
In this study, a spool actuating mechanism using controlled pressure difference is proposed for a large hydraulic servo valve. The actuating mechanism is accomplished by tuning magneto-rheological (MR) fluid flow.
Fan Wang, Ning Guo, Linxiang Wang
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Innovative design tool for the optimization of blast-enhanced facade systems

open access: yesJournal of Facade Design and Engineering, 2015
In current blast enhancement design strategies, to resist the effects of an accidental explosion, a facade system is commonly designed to behave in-elastically and undergo large deformations. The large deformation of the facade system leads to high blast
Marc Zobec   +4 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades

open access: yesJournal of Facade Design and Engineering, 2014
Corresponding author: Jonas Dispersyn, Laboratory for Research on Structural Models (LMO), Department of Structural Engineering, Faculty of Engineering and Architecture, Ghent University, Ghent, Belgium.
Jonas Dispersyn   +3 more
doaj  

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