Results 81 to 90 of about 14,728,610 (293)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Journal of Engineering, 2018 A highly efficient integrated transmission unit – external generating wave movable teeth transmission − was proposed and two kinds of typical transmission types were researched.
Yali Yi, Yunfei Gao, Rui Wei, Herong Jin
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
TEC – Thin Environmental Cladding
Journal of Facade Design and Engineering, 2014 Corresponding author: Alan Tomasi, Group R&D Project Manager, Permasteelisa S.p.A., viale E. Mattei 21/23 | 31029 Vittorio Veneto, Treviso, Italy. Tel.: +39 0438 505207; E-mail: a.tomasi@permasteelisagroup.com; www.permasteelisagroup.com Permasteelisa ...
Alan Tomasi +4 more
doaj
Perception of Complexity in Engineering Design
Systems Engineering, 2021 This paper evaluates perception of complexity in a novel explanatory model that relates product performance and engineering effort. Complexity is an intermediate factor with two facets: it enables desired product performance but also requires effort to achieve.
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Droplet dynamics on slippery surfaces: small droplet, big impact
Biosurface and Biotribology, 2019 The dynamic interaction of droplets with slippery surfaces is essential to various industrial applications, such as anti-icing, water-repellency or water-harvesting, anti-bacterial, and phase change heat transfer.
Yahua Liu +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Journal of Engineering, 2018 The magnetic-liquid suspension guide-way (MLSG) adopts the double support form of permanent magnetic suspension and hydrostatic pressure. It can greatly enhance the bearing capacity and rigidity of the guide-way system.
Jianhua Zhao +4 more
doaj +1 more source
Context-aware synthetic biology by controller design: Engineering the mammalian cell. [PDF]
Cell Syst, 2021 Shakiba N +3 more
europepmc +1 more source