Results 61 to 70 of about 14,728,610 (293)

Effect of design and kinematic parameters on energy requirement in inclined screw mixer

Advanced Engineering Research, 2018
Introduction. Rational parameters and modes of an inclined batch screw mixer are validated to achieve the lowest energyintensive feed mixing under observance of the zootechnical requirements for the feed quality on uneven mixing.
V. F. Khlystunov, S. V. Braginets, A. S. Alferov, M. V. Chernutskiy   +3 more
doaj   +1 more source

Linking design, analysis, manufacture and test in the engineering student experience [PDF]

, 2011
The modern engineer needs to have diverse skills ranging from abilities in re-design, co-design, customisation, management of resources and intellectual property, combined with technical expertise.
Aurisicchio, M, Childs, PRN, McGlashan, N, Gosling, G   +3 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

TECHNOLOGY OF ART AND DESIGN ANALYSIS ON THE CASE STUDY MALE DAGHESTAN NATIONAL COSTUME

Вестник Дагестанского государственного технического университета: Технические науки, 2016
The article considers the stages of artistic analysis of masculine humeral service widespread on the territory of Daghestan in the nineteenth and early twentieth centuries. For example Circassian presents illustrative material: photos, technical drawing,
T. M. Serova
doaj   +1 more source

Engineering Design and Society [PDF]

SSRN Electronic Journal, 2017
As a discipline, engineering is rooted in mathematics and natural sciences; as a practice, it is social at its core. Social science is a more recent development than the society that it seeks to document and understand. Bringing social science into engineering design has its pros and cons.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Systems Engineering Hackathon – A Methodology Involving Multiple Stakeholders to Progress Conceptual Design of a Complex Engineered Product

IEEE Access, 2018
This paper describes a novel hackathon-style system engineering process and its value as an agile approach to the rapid generation and development of early design concepts of complex engineered products-in this case a future aircraft.
S. Saravi, D. Joannou, R. S. Kalawsky, M. R. N. King, I. Marr, M. Hall, P. C. J. Wright, R. Ravindranath, A. Hill   +8 more
doaj   +1 more source

Flexible gypsum mould applied in the mechanical system for blank of grouted ceramic handicrafts based on the radial movement of the sphere and connection by the principle of six-point positioning

The Journal of Engineering, 2020
In order to solve the problems of low production efficiency, poor quality of blanks, high labour intensity and inability to meet the market demand with the manual gypsum mould, a novel design of the gypsum mould to be applied into the automatic ...
Gu Lizhi, Huang Ehui, Song Jinling, Xu Jianmin, Zeng Nianfu, Fang Yuhao, Sun Wei, Chen Zhenhua   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source