Results 51 to 60 of about 14,728,610 (293)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Thermal and lighting perception in four fully glazed office buildings in Santiago, Chile

open access: yesJournal of Facade Design and Engineering, 2013
Corresponding author: Claudio Vásquez, School of Architecture, Catholic University of Chile. 1916 El Comendador str. Providencia, Santiago, ZIP: 7530091, Chile. Tel.: +56 9 92826305; E-mail: clvasque@uc.cl This paper is part of a general research project
Claudio Vásquez   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

What are the Characteristics of Engineering Design Processes? [PDF]

open access: yes, 2011
This paper studies the characteristic properties of Engineering Design (ED) processes from a process modelling perspective. In a first step, we extracted nine characteristics of engineering design processes from the literature and in a second step ...
Maier, Anja   +2 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Improved knowledge management through first-order logic in engineering design ontologies [PDF]

open access: yes, 2010
This paper presents the use of first-order logic to improve upon currently employed engineering design knowledge management techniques. Specifically, this work uses description logic in unison with Horn logic, to not only guide the knowledge acquisition ...
Ian R. Grosse   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Hybrid Quadra‐Tied Solar PV System With Optimised Metaheuristic MPPT Algorithms for Enhanced Urban Rooftop Performance

open access: yesDigital Twins and Applications
This research work helps in selecting the most appropriate combination of solar photovoltaic (SPV) array configuration and metaheuristic MPPT technique to reduce the power loss in rooftop SPV systems due to partial shading conditions caused due to tall ...
Abhinav Bhattacharjee, Suresh Mikkili
doaj   +1 more source

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