Results 91 to 100 of about 4,675,322 (307)
Engineering design project : series 2 [PDF]
, 2017 This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
core
Failure is an option:an innovative engineering curriculum [PDF]
, 2018 PurposeAdvancements and innovation in engineering design are based on learning from previous failures but students are encouraged to ‘succeed’ first time and hence can avoid learning from failure in practice.
Bradley, David +2 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Droplet dynamics on slippery surfaces: small droplet, big impact
Biosurface and Biotribology, 2019 The dynamic interaction of droplets with slippery surfaces is essential to various industrial applications, such as anti-icing, water-repellency or water-harvesting, anti-bacterial, and phase change heat transfer.
Yahua Liu +3 more
doaj +1 more source
SciTech News Volume 71, No. 1 (2017) [PDF]
, 2017 Columns and Reports From the Editor 3 Division News Science-Technology Division 5 Chemistry Division 8 Engineering Division Aerospace Section of the Engineering Division 9 Architecture, Building Engineering, Construction and Design Section of the ...
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Journal of Engineering, 2018 The magnetic-liquid suspension guide-way (MLSG) adopts the double support form of permanent magnetic suspension and hydrostatic pressure. It can greatly enhance the bearing capacity and rigidity of the guide-way system.
Jianhua Zhao +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Analysis and experimental validation of a pressure control method using magneto-rheology fluid flows
The Journal of Engineering, 2018 In this study, a spool actuating mechanism using controlled pressure difference is proposed for a large hydraulic servo valve. The actuating mechanism is accomplished by tuning magneto-rheological (MR) fluid flow.
Fan Wang, Ning Guo, Linxiang Wang
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source