Results 91 to 100 of about 5,340,578 (302)

The Usage and Evaluation of Anthropomorphic Form in Robot Design [PDF]

, 2009
There are numerous examples illustrating the application of human shape in everyday products. Usage of anthropomorphic form has long been a basic design strategy, particularly in the design of intelligent service robots.
Choi, Jeong-gun, Kim, Myungsuk
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Interaction Design in Distributed Software Development: What we know and what we don’t know

Journal on Interactive Systems
Human-Computer Interaction (HCI) is an area focused on human interaction with/through computational systems, among which tangent studies on interaction design stand out.
Daniel Domingos Alves, Ecivaldo de Souza Matos   +1 more
doaj   +1 more source

What Is It Like to Be a Game?—Object Oriented Inquiry for Games Research, Design, and Evaluation

Frontiers in Computer Science, 2020
Human-Computer Interaction (HCI) researchers more and more challenge the notion of technologies as objects and humans as subjects. This conceptualization has led to various approaches inquiring into object perspectives within HCI.
Katta Spiel, Katta Spiel, Katta Spiel, Lennart E. Nacke, Lennart E. Nacke   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Designing For Conversational Interaction

, 2009
In this paper we describe an interaction framework whichclassifies musicians' interactions with virtual musical instruments into three modes: instrumental, ornamental andconversational. We argue that conversational interactionsare the most difficult to design for, but also the most interesting. To illustrate our approach to designing for conversational
Johnston, Andrew, Candy, Linda, Edmonds, Ernest   +2 more
openaire   +1 more source

GazeDrone: Mobile Eye-Based Interaction in Public Space Without Augmenting the User [PDF]

, 2018
Gaze interaction holds a lot of promise for seamless human-computer interaction. At the same time, current wearable mobile eye trackers require user augmentation that negatively impacts natural user behavior while remote trackers require users to ...
Amos B., Camera H., Drewes H., Majaranta P., Plus H., Risko E. F., Sugioka A., Telecommunications N.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source