Results 91 to 100 of about 14,534,189 (338)

Interactive freehand sketching as the means for online communication of design intent in conceptual design conducted by Brainwriting. [PDF]

Int J Interact Des Manuf, 2021
Rizzuti S, De Napoli L.
europepmc   +1 more source

Energy Efficient Engine (E3) combustion system component technology performance report [PDF]

The Energy Efficient Engine (E3) combustor effort was conducted as part of the overall NASA/GE E3 Program. This effort included the selection of an advanced double-annular combustion system design. The primary intent of this effort was to evolve a design
Burrus, D. L., Chahrour, C. A., Foltz, H. L., Sabla, P. E., Seto, S. P., Taylor, J. R.   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Paramounts of Intent-based Networking: Overview

Elektronika ir Elektrotechnika
This study is an exploration of the design of the state-of-the-art intent-based networking (IBN) model. In IBN, communication means are initialised by user’s (herein IT staff, not end-user) input of requirements and not instructions.
Martins Mihaeljans, Andris Skrastins, Jurgis Porins   +2 more
doaj   +1 more source

Penerapan terapi suportif dengan teknik bimbingan untuk mengurangi dorongan bunuh diri pada pasien skizofrenia

Teraputik: Jurnal Bimbingan dan Konseling, 2017
Penelitian ini menyelidiki kondisi pasien skizofrenia tipe paranoid yang memiliki dorongan bunuh diri tinggi yang ditandai gejala depresi dan gangguan mental; putus asa dan merasa tidak berdaya; kejadian negatif dalam hidup; isolasi sosial; disfungsi ...
Sulastry Pardede
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Impact of single classroom-based peer-led organ donation education exposure on high-school students and their families

Indian Journal of Transplantation, 2019
Aims: The aim of the study is to assess the impact of single classroom-based, organ donation education session by high-school students on improvement in knowledge and intent to donate organs in their peers and their families.
Lakshya Aggarwal, Smita Mishra, Manish Agrawal, Dheeraj Shah   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Impressionistic techniques applied in sound art & design [PDF]

, 2018
Sound art and design collectively refer to the process of specifying, acquiring, manipulating or generating sonic elements to evoke emotion and environment.
Sapp, Kaitlyn E. M.
core