Results 151 to 160 of about 160,351 (260)

A social cognitive perspective on teacher technology self-efficacy, inclusion, and student aspirations. [PDF]

BMC Psychol
Lei H, Na F, Lu L, Soomro HJ, Zaigham GHK.   +4 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Autologous Patch Healing vs Secondary Intent Healing after Mohs Micrographic Surgery: A Randomized Controlled Trial. [PDF]

Acta Derm Venereol
Hjorth MK, Burian EA, Karlsmark T, Mogensen M, Glud M, Harager AA, Rossi A, Karmisholt KE.   +7 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Best Practice: CT-guided Adaptive Radiotherapy Reference Planning on the Ethos Platform. [PDF]

J Appl Clin Med Phys
Ray X, Harms J, Price A, Lin MH, Stanley DN.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Large Language Model Chatbot Conversations vs Public Health Materials and Parental HPV Vaccination Intentions: A Randomized Clinical Trial.

JAMA Netw Open
Sehgal NKR, Rai S, Tonneau M, Agarwal AK, Cappella J, Kornides ML, Ungar L, Buttenheim A, Guntuku SC.   +8 more
europepmc   +1 more source

A Bi-lingual chatbot implementation for pandemic response using the transformer-based approach. [PDF]

PLOS Digit Health
Atwine MT, Jjingo D, Nsubuga M, Serunjogi R, Mbabaali I, Lujumba I, David B, Kintu T, Galiwango R, Grace K.   +9 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Reclassifying contralateral axillary metastasis: survival benefit of aggressive local therapy challenges stage IV designation. [PDF]

Front Oncol
Liu S, Li Y, Shen Y, Mao Q, Li L.
europepmc   +1 more source