Results 31 to 40 of about 2,087,196 (218)

Designing knowledge-rich curricula [PDF]

open access: yes, 2008
What role does knowledge have in competency based higher education? Many Dutch Universities of Professional Education are struggling with the implementation of competency-based curricula. In view of current practice, this article distinguishes between two sorts of knowledge: vocation-related knowledge and context-free knowledge.
Hezemans, M., Ritzen, M.
openaire   +3 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Applying Design Knowledge to Programming [PDF]

open access: yes, 2011
Arguably programming involves design: computational logic – the program – is constantly reorganized to keep complexity manageable and provide for current and future coding activities to be feasible. However, design practices have gained less attention in the field of programming, even though decades of research on design have led to a large body of ...
Steinert, Bastian, Hirschfeld, Robert
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Roles of design knowledge in knowledge-based systems

open access: yesInternational Journal of Human-Computer Studies, 1996
Abstract Recent research suggests that the abilities of a knowledge-based system (KBS) depend in part on the amount of explicit knowledge it has about the way it is designed. This knowledge is often called design knowledge because it reflects design decisions that a KBS developer makes regarding what ontologies to embody in the system, what solution ...
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modeling Knowledge Work for the Design of Knowledge Infrastructures

open access: yesJ. Univers. Comput. Sci., 2005
JUCS - Journal of Universal Computer Science Volume Nr.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy