Results 71 to 80 of about 17,541,500 (288)
Perceived Culture of Networked Knowledge Hubs
, 2019 While the construction of knowledge hubs has gained recent traction, little is known on how networked actors perceive their collective culture. Authors looked at the topic through a single case study, the Design Factory Global Network, a network of 24 ...
Mikkonen, Maria +2 more
core +1 more source
Workshop design for enhancing the appropriateness of idea generation using analogical thinking
International Journal of Innovation Studies, 2017 As technologies advance and replace human labor in a variety of settings, we focus our attention on human creativity for generating new ideas. Business organizations, more than ever, recognize that they need employees who think creatively to maintain ...
Eunyoung Kim
doaj +1 more source
Designing knowledge-rich curricula [PDF]
, 2008 What role does knowledge have in competency based higher education? Many Dutch Universities of Professional Education are struggling with the implementation of competency-based curricula. In view of current practice, this article distinguishes between two sorts of knowledge: vocation-related knowledge and context-free knowledge.
Hezemans, M., Ritzen, M.
openaire +4 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
4D, 2018 In this paper I will put forward some aspects of the position Central and Eastern Europe in the European history of landscape architecture, with a special focus on Hungary (this time especially on the historical Hungary).
Martin Van den Toorn
doaj
Applying Design Knowledge to Programming [PDF]
, 2011 Arguably programming involves design: computational logic – the program – is constantly reorganized to keep complexity manageable and provide for current and future coding activities to be feasible. However, design practices have gained less attention in the field of programming, even though decades of research on design have led to a large body of ...
Steinert, Bastian, Hirschfeld, Robert
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Frontiers in Public HealthBackgroundThis narrative review examines the barriers and opportunities that shape access and delivery of cervical cancer care services in sub-Saharan Africa.
Netsanet Mengistie +6 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Representation and Use of Design Knowledge in Evolutionary Design
, 1995 This paper describes an approach to knowledge representation for an evolutionary design process. The concept of design schemas is introduced to provide the representational framework for design knowledge.
J. Jo, J.S. Gero
core