Results 81 to 90 of about 17,541,500 (288)

Constraint-Aided Product Design

open access: yesActa Polytechnica, 2005
The importance of supporting the early stages of design is widely accepted. In particular, the development of supportive tools and methods for modelling and analysis of evolving design solutions present a difficult challenge.
G. Mullineux, B. Hicks, T. Medland
doaj  

Mitigating the hardness loss due to divorced eutectoid transformation in pearlitic steels: Influence of the cooling rate and austenitization temperature

open access: yesEuropean Journal of Materials
Divorced eutectoid transformation (DET) in pearlitic steels results in spheroidized cementite morphology instead of characteristic lamellar structure of pearlite.
Oleksandr Glushko   +4 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A Computer-Supported Framework for Form Analysis [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics
Although there are several frameworks for the synthesis of form, and for the automated development of geometric shapes, studies in the systematic analysis of architectural forms and their automation are still underrepresented.
Buthayna Eilouti
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Navigating Conflicting Interests: The Role of Gender Competent Management for Effective Gender Equality Plans

open access: yesSocial Inclusion
The Horizon Europe mandate requiring Gender Equality Plans (GEPs) for funding eligibility has initiated a veritable wave of documented initiatives across research performing organisations (RPOs).
Angela Wroblewski, Karin Grasenick
doaj   +1 more source

Modeling Knowledge Work for the Design of Knowledge Infrastructures

open access: yesJ. Univers. Comput. Sci., 2005
JUCS - Journal of Universal Computer Science Volume Nr.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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