Results 81 to 90 of about 7,304,657 (316)

Navigating Conflicting Interests: The Role of Gender Competent Management for Effective Gender Equality Plans

open access: yesSocial Inclusion
The Horizon Europe mandate requiring Gender Equality Plans (GEPs) for funding eligibility has initiated a veritable wave of documented initiatives across research performing organisations (RPOs).
Angela Wroblewski, Karin Grasenick
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Adopting Hybrid Integrated Flexible Electronics in Products: Case—Personal Activity Meter

open access: yesIEEE Journal of the Electron Devices Society, 2019
In this case study, the possibilities of hybrid integration of printed and flexible electronics in combination with conventional electronic components to create new types of product concepts is demonstrated.
Terho Kololuoma   +12 more
doaj   +1 more source

Adaptation and implementation of a process of innovation and design within a SME [PDF]

open access: yes, 2014
A design process is a sequence of design phases, starting with the design requirement and leading to a definition of one or several system architectures. For every design phase, various support tools and resolution methods are proposed in the literature.
AMMAR, Adel Amin   +2 more
core  

Knowledge Acquisition Design Framework

open access: yes, 2021
Knowledge acquisition design is a framework for transdisciplinary co-production research of scientific and technological knowledge.
Alvares, Lillian Maria Araujo de Rezende   +1 more
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Constraint-Aided Product Design

open access: yesActa Polytechnica, 2005
The importance of supporting the early stages of design is widely accepted. In particular, the development of supportive tools and methods for modelling and analysis of evolving design solutions present a difficult challenge.
G. Mullineux, B. Hicks, T. Medland
doaj  

Representing and Capturing the Experts´ Knowledge in a Design Process [PDF]

open access: yes, 2003
An object-oriented framework to support the modeling and management of the design process is introduced. It naturally integrates the representation of both the design process itself, and the outcomes that are achieved as the result of the various design ...
Gonnet, Silvio Miguel   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Knowledge modeling for software design [PDF]

open access: yes
This paper develops a modeling framework for systems engineering that encompasses systems modeling, task modeling, and knowledge modeling, and allows knowledge engineering and software engineering to be seen as part of a unified developmental process ...
Gaines, Brian R., Shaw, Mildred L. G.
core   +1 more source

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