Results 101 to 110 of about 17,541,500 (288)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Quality Control Methods Using Quality Characteristics in Development and Operations
DigitalSince the Software Quality Model was defined as an international standard, many quality assurance teams have used this quality model in a waterfall model for software development and quality control.
Daiju Kato, Hiroshi Ishikawa
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Frontiers in MedicineBackgroundLate-life depression is a growing public health challenge in aging societies. Community parks are increasingly recognized as protective environments, yet evidence on which specific attributes most effectively alleviate depression among older ...
Zhi-Hao Zhang +2 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Scientific ReportsThe announcement of LK-99 as a potential room-temperature, ambient-pressure superconductor sparked widespread debate across both traditional news outlets and social media platforms.
Eunhye Kim, Wei Luo, Hunkoog Jho
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Design and Development of Iranian Institutional Repositories Integrated Search (IRIS) Portal
Iranian Journal of Information Processing & Management, 2021 The purpose of this research is to design and develop an integrated open portal for searching and retrieving information of institutional repositories of universities, and higher education and research institutes in Iran.
Bahareh Pahlevanzadeh +1 more
doaj
Design & knowledge modeling - Knowledge modeling as design
, 1993 The paper presents a cognitive analysis of design as a problem-solving activity. Design is characterized through results from empirical studies of various design tasks. Based on this characterization, it will be argued why and how knowledge modeling can be considered as a design task.
openaire +1 more source