Results 101 to 110 of about 7,304,657 (316)
The elements of design knowledge capture [PDF]
This paper will present the basic constituents of a design knowledge capture effort. This will include a discussion of the types of knowledge to be captured in such an effort and the difference between design knowledge capture and more traditional ...
Freeman, Michael S.
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Applying Design Knowledge to Programming [PDF]
, 2011 Arguably programming involves design: computational logic – the program – is constantly reorganized to keep complexity manageable and provide for current and future coding activities to be feasible. However, design practices have gained less attention in the field of programming, even though decades of research on design have led to a large body of ...
Steinert, Bastian, Hirschfeld, Robert
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Roles of design knowledge in knowledge-based systems
International Journal of Human-Computer Studies, 1996 Abstract Recent research suggests that the abilities of a knowledge-based system (KBS) depend in part on the amount of explicit knowledge it has about the way it is designed. This knowledge is often called design knowledge because it reflects design decisions that a KBS developer makes regarding what ontologies to embody in the system, what solution ...
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Modeling Knowledge Work for the Design of Knowledge Infrastructures
J. Univers. Comput. Sci., 2005 JUCS - Journal of Universal Computer Science Volume Nr.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in MedicineBackgroundLate-life depression is a growing public health challenge in aging societies. Community parks are increasingly recognized as protective environments, yet evidence on which specific attributes most effectively alleviate depression among older ...
Zhi-Hao Zhang +2 more
doaj +1 more source
Design and Development of Iranian Institutional Repositories Integrated Search (IRIS) Portal
Iranian Journal of Information Processing & Management, 2021 The purpose of this research is to design and develop an integrated open portal for searching and retrieving information of institutional repositories of universities, and higher education and research institutes in Iran.
Bahareh Pahlevanzadeh +1 more
doaj
Representation and matching of knowledge to design digital systems [PDF]
, 1988 A knowledge-based expert system is described that provides an approach to solve a problem requiring an expert with considerable domain expertise and facts about available digital hardware building blocks.
Jones, J. U., Shiva, S. G.
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