Results 241 to 250 of about 3,979,734 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

TopoDoE: a design of experiment strategy for selection and refinement in ensembles of executable gene regulatory networks. [PDF]

open access: yesBMC Bioinformatics
Bouvier M   +6 more
europepmc   +1 more source

Designer experience

CHI '11 Extended Abstracts on Human Factors in Computing Systems, 2011
User-Centered Design (UCD) under the umbrella of user experience (UX) has gained momentum as the de facto standard to produce successful products and services. Use of products is seen as a highly personal and context-sensitive balancing act that derives its uniqueness from the actions and emotions of the users.
Mika P. Nieminen   +3 more
openaire   +1 more source

Experience design for dummies

Proceedings of the 15th European conference on Cognitive ergonomics: the ergonomics of cool interaction, 2008
In this paper we explore the concept of experience and develop premises for the design for experience. In industrial practice designers frequently lack sufficient expertise to design for experience. We provide a view on how to support the design for experience in those cases where a single designer or a design team is not fully equipped to do the job ...
Oppelaar, E.J.R.G.   +2 more
openaire   +2 more sources

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