Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Design and Experiment of an Unoccupied Control System for a Tracked Grain Vehicle. [PDF]
Pan J +7 more
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Integrated Design and Experiment of a Micro-Vibration Isolation and Pointing Platform for Large Space Optical Payloads Based on Voice Coil Motors. [PDF]
Guo Y, Zhou J, Gao Z, Feng B, Xu M.
europepmc +1 more source
Optimization design and experiment of key components of mountain pendulum-lever cam type hole seeders based on DEM-MBD coupling simulation. [PDF]
Zhao L +9 more
europepmc +1 more source
TopoDoE: a design of experiment strategy for selection and refinement in ensembles of executable gene regulatory networks. [PDF]
Bouvier M +6 more
europepmc +1 more source
Optimization of Glibenclamide Loaded Thermoresponsive SNEDDS Using Design of Experiment Approach: Paving the Way to Enhance Pharmaceutical Applicability. [PDF]
Sherif AY, Elzayat EM, Altamimi MA.
europepmc +1 more source
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In this paper we explore the concept of experience and develop premises for the design for experience. In industrial practice designers frequently lack sufficient expertise to design for experience. We provide a view on how to support the design for experience in those cases where a single designer or a design team is not fully equipped to do the job ...
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