Results 41 to 50 of about 4,507,524 (283)

Modelling multi-tier enterprise applications behaviour with design of experiments technique [PDF]

, 2015
Queueing network models are commonly used for performance modelling. However, through application development stage analytical models might not be able to continuously reflect performance, for example due to performance bugs or minor changes in the ...
Jamshidi, P, Ustinova, T
core   +2 more sources

Development of an empirical model for copper extraction from chalcocite in chloride media [PDF]

Hemijska Industrija, 2020
Multivariate models are a useful tool when studying the effects of independent variables on one or more dependent variables, since this approach allows modeling of the dynamics of complex systems based on simple analytical models with considerable ...
Saldaña Manuel, Rodríguez Freddy, Rojas Anyelo, Pérez Kevin, Angulo Palma Hugo Javier   +4 more
doaj   +1 more source

Design of Experiments for Screening

, 2015
The aim of this paper is to review methods of designing screening experiments, ranging from designs originally developed for physical experiments to those especially tailored to experiments on numerical models. The strengths and weaknesses of the various
A Boukouvalas, A Marrel, A Miller, A Saltelli, A Saltelli, A.E. Vine, AB Owen, AC Atkinson, AM Dean, B Abraham, B Bettonvil, B Bettonvil, B. Tang, B. Tang, BA Jones, BA Jones, BA Jones, C Daniel, C Linkletter, C.F.J. Wu, C.F.J. Wu, CA Mauro, CE Rasmussen, CJ Marley, CR Rao, CS Cheng, D Draguljić, D Dupuy, D Scott-Drechsel, D. Xing, D.T. Voss, DA Bulutoglu, DJ Finney, DKJ Lin, DKJ Lin, EI George, F Campolongo, F Campolongo, F Satterthwaite, FKH Phoa, FKH Phoa, G Damblin, G Pujol, G.S. Watson, GEP Box, GEP Box, GEP Box, GEP Box, GM James, H Moon, H. Wan, H. Xu, H. Yang, H.B.E. Wan, HA Chipman, JL Loeppky, JPC Kleijnen, K.Q. Ye, KHV Booth, KJ Ryan, KP Burnham, KT Fang, L Pronzato, L. Xiao, M Claeys-Bruno, M Hamada, M Hamada, M Johnson, M Liu, M.A. Wolters, MD McKay, MD Morris, MD Morris, MD Morris, MJ Hall, N Durrande, NA Butler, NK Nguyen, NK Nguyen, NK Nguyen, PR Scinto, PZG Qian, PZG Qian, PZG Qian, R Dorfman, R Jin, R Joseph, RB Gramacy, RK Meyer, RL Iman, RL Plackett, RV Lenth, S Ba, SC Cotter, SG Gilmour, SM Lewis, TJ Santner, VE Bowman, W DuMouchel, W Li, W.J. Welch, WA Brenneman, WW Li, X Qu, Y Benjamini, Y Liu   +105 more
core   +1 more source

Application of the experimental design for the analysis of nonattendance to scheduled medical appointments in the Colombian Health System

Dyna, 2022
This paper shows a study about nonattendance to medical appointments in the Colombian health system to determine which strategies have the greatest effect on the response variable (nonattendance) of scheduled medical appointments.
Elisa del Carmen Navarro Romero, Natalia García-Corrales, Óscar Mauricio Gelves-Alarcón, Wilfrido Javier Arteaga-Sarmiento   +3 more
doaj   +1 more source

The importance of design of experiments [PDF]

Mining and Metallurgy Engineering Bor
Design of experiments (DOE) is very meaningful and applied in various investigations from science to the industry in order to optimize the process itself.
Milosavljević Aleksandra, Pavlov-Kagadejev Marijana, Stolić Predrag   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Systematic optimization of human pluripotent stem cells media using Design of Experiments. [PDF]

, 2015
Human pluripotent stem cells (hPSC) are used to study the early stages of human development in vitro and, increasingly due to somatic cell reprogramming, cellular and molecular mechanisms of disease.
Chailangkarn, Thanathom, Marinho, Paulo A, Muotri, Alysson R   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source