Results 41 to 50 of about 4,561,954 (333)

Aspects and Implementation of Pharmaceutical Quality by Design from Conceptual Frameworks to Industrial Applications

Pharmaceutics
Background/Objectives: Quality by Design (QbD) has revolutionized pharmaceutical development by transitioning from reactive quality testing to proactive, science-driven methodologies.
Shiwei Yang, Xingming Hu, Jinmiao Zhu, Bin Zheng, Wenjie Bi, Xiaohong Wang, Jialing Wu, Zimeng Mi, Yifei Wu   +8 more
doaj   +1 more source

Human Perception Measures for Product Design and Development—A Tutorial to Measurement Methods and Analysis

Multimodal Technologies and Interaction, 2017
This tutorial describes the necessary steps for designing and conducting a perception experiment in order to obtain design parameters for human–machine interactions.
Christian Hatzfeld, Manuel Kühner, Stefan Söllner, Tran Quoc Khanh, Mario Kupnik   +4 more
doaj   +1 more source

On the design of experiments to study extreme field limits

, 2012
We propose experiments on the collision of high intensity electromagnetic pulses with electron bunches and on the collision of multiple electromagnetic pulses for studying extreme field limits in the nonlinear interaction of electromagnetic waves.
Bulanov, S. S., Bulanov, S. V., Chen, M., Chen, P., Esarey, E., Esirkepov, T. Zh., Kando, M., Koga, J. K., Korn, G., Leemans, W. P., Mur, V. D., Narozhny, N. B., Popov, V. S., Schroeder, C. B., Thomas, A. G. R., Zhidkov, A. G.   +15 more
core   +1 more source

Design of experiments for non-manufacturing processes : benefits, challenges and some examples [PDF]

, 2010
Design of Experiments (DoE) is a powerful technique for process optimization that has been widely deployed in almost all types of manufacturing processes and is used extensively in product and process design and development.
Anderson, M. J., Antony, J., Coleman, S., Montgomery, D. C., Silvestrini, R. T.   +4 more
core   +2 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

TEACHING SOFTWARE FOR DESIGNING OF EXPERIMENTS (DOE) IN WOODWORKING PROCESSES [PDF]

Pro Ligno, 2015
This paper presents a teaching software that allows students and researchers to understand how passive and active experiments can be made, without making real experiments.
Wilhelm LAURENZI
doaj  

Optimal design of dilution experiments under volume constraints [PDF]

, 2013
The paper develops methods to construct a one-stage optimal design of dilution experiments under the total available volume constraint typical for bio-medical applications.
Zolghadr, Maryam, Zuyev, Sergei
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Optimization of the Tensile Properties of Polymeric Matrix Composites Reinforced with Magnetite Particles by Experimental Design

TecnoLógicas, 2020
A full-factorial 33 experiment was used in this study to determine the optimal values of the tensile properties of three composite materials manufactured based on three polymeric resins: Derakane Momentum epoxy vinyl ester based on bisphenol-A (DM-411 ...
Luis Ángel Lara-González, Wilmar Guillermo-Rodríguez, Yaneth Pineda-Triana, Gabriel Peña-Rodríguez, Hugo Felipe Salazar   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source