Results 121 to 130 of about 903,165 (318)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Application of optimization algorithms in the design of a superconducting A.C. generator rotor [PDF]
, 1990 The superconducting a.c. generator is expected to be the optimum choice among a.c. generation systems in future because of its reduced size, high efficiency, high terminal voltage and its contribution to the stability of the power system.
Safi, Sabah K.
core
Improved marine predator MPPT algorithm for photovoltaic systems in partial shading conditions
Scientific ReportsWhen the photovoltaic arrays are subject to partial shading (PS), their output characteristics show a multi-peak phenomenon. Under this circumstance, it will be a challenge to track the maximum power point (MPP), which impacts power generation efficiency.
Hanbo Zheng +5 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Comparison of Direct Multiobjective Optimization Methods for the Design of Electric Vehicles [PDF]
, 2006 "System design oriented methodologies" are discussed in this paper through the comparison of multiobjective optimization methods applied to heterogeneous devices in electrical engineering.
Régnier, Jérémi +3 more
core
Distributed Synchronization Control to Trajectory Tracking of Multiple Robot Manipulators
Journal of Robotics, 2011 This paper investigates the issue of designing decentralized control laws to cooperatively command a team of general fully actuated manipulators. The purpose is to synchronize their movements while tracking a common desired trajectory.
Yassine Bouteraa +3 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
, 2012 This paper presents a comparison between different multiobjective optimization approaches that can be used to optimize the design of thermal equipment. Plate heat exchanger is taken as case study to apply different optimization techniques.
Aute, Vikrant +3 more
core
Set-based design of mechanical systems with design robustness integrated
, 2014 This paper presents a method for parameter design of mechanical products based on a set-based approach. Set-based concurrent engineering emphasises on designing in a multi-stakeholder environment with concurrent involvement of the stakeholders in the ...
DANTAN, Jean-Yves +3 more
core +1 more source