Results 141 to 150 of about 598,406 (269)

Correction: Advances in the structures, mechanisms and targeting of molecular chaperones

Signal Transduction and Targeted Therapy
Jinying Gu, Yanyi He, Chenxi He, Qiuyue Zhang, Qifei Huang, Shangjun Bai, Ruoning Wang, Qidong You, Lei Wang   +8 more
doaj   +1 more source

A sustainable spectrofluorimetric method for ivabradine quantification based on erythrosin B quenching with quantum mechanical modeling and Box-Behnken design optimization. [PDF]

RSC Adv
Alqahtani AS, Abduljabbar MH, Alnemari RM, Althobaiti MM, Aldawsari MF, Al-Mutairi AA, Serag A, Almalki AH.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Progress and Perspectives on Heat Transfer Design Optimization of Functionally Graded Materials Under Large Temperature Gradients. [PDF]

Materials (Basel)
Zhang F, Shen Y, Yang H.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Green Synthesis and Quality-by-Design Optimization of <i>Dacryodes edulis</i>-Derived Silver Nanoparticles with Broad-Spectrum Antiviral and Antimicrobial Activity. [PDF]

Molecules
Xulu JH, Tembu VJ, Moeno S, Tsakem B, Thibane VS, Witika BA, Siwe Noundou X.   +6 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Design, optimization and controllability analysis of an improved sulfur recovery unit based on SuperClaus process. [PDF]

Sci Rep
Kazemi T, Eslamloueyan R.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Corrigendum to “Data driven analysis of social capital in Farmer Producer Companies” [Heliyon Volume 9, Issue 7, July 2023, Article e17489]

Heliyon
Aishwarya Jayaraman, Palaniappan Ramu, Sudhir Chella Rajan, Sidhant PravinKumar Thole   +3 more
doaj   +1 more source