Results 121 to 130 of about 13,502,506 (299)
Design patterns for engineering genetic stability. [PDF]
Curr Opin Biomed Eng, 2021 Son HI, Weiss A, You L.
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modularity Improvement of Design Patterns
Design patterns are known as proven solutions for solving frequently occurring problems in software development. Unfortunately, they do not fully correspond to modularity principles, and their implementations are usually not considered to be reusable ...
Kotovs, Vladimirs
core
Miyazaki's graphic novels: patterns in design
, 2010 This thesis examines patterns in the design choices of Hayao Miyazaki in Nausicay of the Valley of the Wind. It addresses a gap in the research about graphic novels by focusing on patterns that relate to comic art as a genre, patterns that recall various
Ewald, James
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The discourse of design: Patterns of TPACK Contribution during pre-service teacher learning design conversations. [PDF]
Educ Inf Technol (Dordr), 2022 Nguyen GNH, Bower M, Stevenson M.
europepmc +1 more source
Ingeniare: Revista Chilena de Ingeniería, 2006 Este documento presenta una propuesta de cómo integrar adecuadamente diversas tecnologías de persistencia, de negocios y web en una plataforma J2EE. Esto involucra una arquitectura de múltiples capas, que considera para cada capa el uso de soluciones ...
David Colque C, Ricardo Valdivia P
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Method for Building Trustworthy Hybrid Performance Models for Cyber-Physical Systems of Systems
IEEE AccessThe increasing dynamism and interconnectivity of Cyber-Physical Systems of Systems (CPSoS) emphasize the need for advanced performance modeling approaches.
Mahtab Modaber +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source