Results 81 to 90 of about 21,433,054 (296)

Some azine and azole derivatives as antioxidant additives for lithium lubricating grease

Egyptian Journal of Petroleum, 2013
Lubricating greases undergo extensive deterioration under the operation conditions and storage. Hydrocarbon chain is one of the major factors resulting in loss of the base fluid quality by formation of products having negative effects on the ...
Reda M. Fikry, Refaat A. El-Adly, Nabila A. Ismail, A.S. El-Tabei, Hend Al-Aidy   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The effect of voltage on accuracy in electrochemical micromachining under two-tone sinusoidal signal

Electrochemistry Communications
Electrochemical micromachining (ECMM) is a non-traditional technology in the field of machining, which has excellent machining quality. Ultra short pulse power supply is widely used in electrochemical micro machining, and shortening the pulse width is ...
Xin Wang, JianChao Xiong, JiPeng Wang, Xi Chen   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Design Sketching Process [PDF]

, 2006
Sketching the what-if situation provided insight into alternative design possibilities, and gave an idea of how the sketched design will work in the context at hand. Though software provided possibilities of creating a high fidelity executable prototype at a very fast pace, here sketches that were non- executable drawings of the envisioned system, are ...
openaire   +1 more source

What is sought from graphic designers? A first thematic analysis of job offers for graphic design positions in the United Kingdom

, 2016
An empirically grounded understanding about which knowledge and skills that are sought from designers is missing for a number of professional subfields of design. This gap in research challenges i) design educators in planning their educational offerings
Person, Oscar, Nicoletti Dziobczenski, Paulo, Dziobczenski, Paulo Roberto Nicoletti, Paulo Roberto Nicoletti Dziobczenski, Oscar Person   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Improving design grammar development and application through network-based analysis of transition graphs

Design Science, 2016
Design grammars enable the formal representation of a vocabulary and rules that describe how designs can be synthesized just as the grammar rules of a spoken language define how to formulate valid, i.e., grammatically correct, sentences.
Corinna Königseder, Tino Stanković, Kristina Shea   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source