Results 91 to 100 of about 4,145,489 (318)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design Science, 2016 Design grammars enable the formal representation of a vocabulary and rules that describe how designs can be synthesized just as the grammar rules of a spoken language define how to formulate valid, i.e., grammatically correct, sentences.
Corinna Königseder +2 more
doaj +1 more source
The Design Sketching Process [PDF]
, 2006 Sketching the what-if situation provided insight into alternative design possibilities, and gave an idea of how the sketched design will work in the context at hand. Though software provided possibilities of creating a high fidelity executable prototype at a very fast pace, here sketches that were non- executable drawings of the envisioned system, are ...
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2009 With rapid growth of global competition, the design process is becoming more and more complex due largely to cross-functional team collaboration, dynamic design processes, and unpredictable design outcomes.
Yin, Yuanyuan
core
EnergiesThis review provides a comprehensive analysis of advanced control strategies and operational optimization of energy systems, focusing on heat pumps, with an emphasis on their role in enhancing energy efficiency and operational flexibility.
Konstantinos Sittas +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Modelling iteration in engineering design
, 2007 This paper examines design iteration and its modelling in the simulation of New Product Development (NPD) processes. A framework comprising six perspectives of iteration is proposed and it is argued that the importance of each perspective depends upon ...
Eckert, C. M. +2 more
core
SeparationsCentrifugal Partition Chromatography (CPC) is a separation technique that utilizes immiscible liquid phases to purify compounds. The selection of solvents in Liquid–Liquid Chromatography offers flexibility and optimization possibilities for specific ...
Felix Buthmann +4 more
doaj +1 more source