Results 131 to 140 of about 7,545,913 (316)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
DIFFICULT FORMS: Critical practices of design and research [PDF]
, 2009 As a kind of ‘criticism from within’, conceptual and critical design inquire into what design is about – how the market operates, what is considered ‘good design’, and how the design and development of technology typically works.
Mazé, Ramia, Redström, Johan
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The use of argumentation in design research
, 2016 This paper proposes argumentation as a key skill that ties research methodology into design. The paper first aligns Toulmin argumentation with the role of design and design results and then provides an example of how this skills set can be acquired in ...
Stella Boess, Boess, Stella
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Bookmaking as Critical and Feminist Practice of Design
, 2018 Arts expansion in academia has called into question concepts, norms and regulations concerning writing and publishing. Given precedents of ‘critical practices of design’ and ‘research through practice’ grappling with such issues, I take these as ways to ...
Maze, Ramia, Ramia Mazé
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Towards sustainable textile materials: Potential Pathways and Dialogues between Disciplines.
, 2019 The need to take care of our material environment has become urgent. New types of scientific collaboration have emerged, and designers are being invited to collaborate with top-level scientists.
Niinimäki, Kirsi, Kääriäinen, Pirjo
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Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Call for Papers for the 1973 Design Activity International Conference
, 1973 The 1973 Design Research Society Conference was held jointly with the US Design Methods Group on 29-31 August 1973 at The Polytechnic of Central London.
Design Research Society and Design Methods Group,
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source