Results 141 to 150 of about 7,545,913 (316)
Data-driven engineering design research: Opportunities using open data [PDF]
, 2017 Engineering Design research relies on quantitative and qualitative data to describe design-related phenomena and prescribe improvements for design practice.
Parraguez Ruiz, Pedro, Maier, Anja
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
In Another Life Another Being: On Design and the Wages of Decoloniality
DiseñaDespite the struggles for design disciplines to confront their colonial legacies and practices, the question remains: who can truly afford a decolonizing practice worthy of the name?
Jomy Joseph
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Towards Translation Design A New Paradigm for Design Research
, 2016 In this paper we explore the concept of translation, starting from the assumption that it constitutes an essential reference for design culture. We assume that a designer (and in particular a communication designer) is a “translator”, since he realises a
Giovanni Baule, Baule, Giovanni
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
, 2021 Designers need to become more comfortable collecting, discussing and using quantitative data to inform and substantiate design decisions in the scoping phase of design projects.
Berry, James (R7281), Lechner, Tyran
core
Participatory design research for the development of real-time simulation models in healthcare. [PDF]
Health Syst (Basingstoke), 2023 Harper A, Mustafee N.
europepmc +1 more source
Facilitating Design Research by Mapping Design Research Trajectories.
, 2014 Design research is an emerging paradigm in the study of learning. It is far from a mature methodology, as it faces a variety of difficulties, one of which is the characterization of the research process. We mapped the design trajectory proposed by Sandoval to capture the complex process of design research.
Ma, G, van Aalst, J
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source