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Methods for Developing a Process Design Space Using Retrospective Data [PDF]

open access: yesPharmaceutics, 2023
Prospectively planned designs of experiments (DoEs) offer a valuable approach to preventing collinearity issues that can result in statistical confusion, leading to misinterpretation and reducing the predictability of statistical models.
Miquel Romero-Obon   +6 more
doaj   +2 more sources

A design space for automated material handling vehicles [PDF]

open access: yesFrontiers in Robotics and AI, 2023
Material Handling Vehicles (loaders, excavators, forklifts, harvesters, etc.) have seen a strong increase in automation efforts in recent years. The contexts such vehicles operate in are frequently complex and due to the often very specific nature of ...
Alexander G. Mirnig   +7 more
doaj   +2 more sources

Wide-address spaces [PDF]

open access: yesACM SIGOPS Operating Systems Review, 1993
In a recent issue of Operating System Review, Hayter and McAuley [1991] argue that future high-performance systems trade a traditional, bus-based organization for one where all components are linked together by network switches (the Desk-Area Network).
Bartoli, Alberto   +3 more
openaire   +8 more sources

Control Strategy for Excipient Variability in the Quality by Design Approach Using Statistical Analysis and Predictive Model: Effect of Microcrystalline Cellulose Variability on Design Space [PDF]

open access: yesPharmaceutics, 2022
Although various quality by design (QbD) approaches have been used to establish a design space to obtain robust drug formulation and process parameters, the effect of excipient variability on the design space and drug product quality is unclear.
Ji Yeon Kim, Du Hyung Choi
doaj   +2 more sources

Design Space and Control Strategy for the Manufacturing of Wet Media Milled Drug Nanocrystal Suspensions by Adopting Mechanistic Process Modeling [PDF]

open access: yesPharmaceutics
Wet media milling is a fully industrialized technology for the manufacturing of drug nanocrystal suspensions. This work describes the development of an advanced control strategy and an associated design space for a manufacturing process at a commercial ...
André Bitterlich   +2 more
doaj   +2 more sources

Design Space Approach for the Optimization of Green Fluidized Bed Granulation Process in the Granulation of a Poorly Water-Soluble Fenofibrate Using Design of Experiment [PDF]

open access: yesPharmaceutics, 2022
In the pharmaceutical industry, the systematic optimization of process variables using a quality-by-design (QbD) approach is highly precise, economic and ensures product quality. The current research presents the implementation of a design-of-experiment (
Mohamed H. Fayed   +3 more
doaj   +2 more sources

Designing Network Design Spaces [PDF]

open access: yes2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2020
CVPR ...
Radosavovic, Ilija   +4 more
openaire   +2 more sources

Study on the Construction Mode of Ecological and Sustainable Rain Flood in New Urban Area of China [PDF]

open access: yesE3S Web of Conferences, 2019
In the background of the urbanization process has exceeded 58% of China and expansion of the construction land expansion, as a future appropriate residential development and ahead of the key area of urban rain flood management, this research expounds the
Kang Caixia   +4 more
doaj   +1 more source

Machine Learning in Structural Design: An Opinionated Review

open access: yesFrontiers in Built Environment, 2022
The prominence gained by Artificial Intelligence (AI) over all aspects of human activity today cannot be overstated. This technology is no newcomer to structural engineering, with logic-based AI systems used to carry out design explorations as early as ...
Christian Málaga-Chuquitaype
doaj   +1 more source

In-Depth Understanding of Granule Compression Behavior under Variable Raw Material and Processing Conditions

open access: yesPharmaceutics, 2022
Tablet manufacturing involves the processing of raw materials through several unit operations. Thus, the mitigation of input-induced variability should also consider the downstream processability of intermediary products.
Tibor Casian   +7 more
doaj   +1 more source

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