Results 111 to 120 of about 5,060,080 (299)
The application of multi-objective robust design methods in ship design [PDF]
, 1999 When designing large complex vessels, the evaluation of a particular design can be both complicated and time consuming. Designers often resort to the use of concept design models enabling both a reduction in complexity and time for evaluation.
Coates, Graham +2 more
core
Formal and Informal Methods for Multi-Core Design Space Exploration
, 2014 We propose a tool-supported methodology for design-space exploration for embedded systems. It provides means to define high-level models of applications and multi-processor architectures and evaluate the performance of different deployment (mapping ...
Kempf, Jean-Francois +2 more
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Testing approaches for global optimization of space trajectories [PDF]
, 2008 In this paper, the procedures to test global search algorithms applied to space trajectory design problems are discussed. Furthermore, a number of performance indexes that can be used to evaluate the effectiveness of the tested algorithms are presented ...
Locatelli, Marco +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
IEEE AccessComprehensive data on machines is essential for digitization in the industry. Since standardized machine elements are used in most machines, integrating them with sensors provides the opportunity to acquire data comprehensively from in-situ.
Julian Peters +6 more
doaj +1 more source
Design considerations for space flight hardware [PDF]
The environmental and design constraints are reviewed along with some insight into the established design and quality assurance practices that apply to low earth orbit (LEO) space flight hardware.
Glover, Daniel
core +1 more source
A novel design concept for space-based polar remote sensing [PDF]
, 2012 Space-based remote sensing of the Earth is conducted from a fleet of spacecraft in two basic orbital positions, near-polar low-Earth orbits and geosynchronous orbits, with each offering its own advantages and disadvantages.
Anderson, Pamela +2 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source