Results 51 to 60 of about 22,992,422 (339)

Application of quality by design approach to optimize process and formulation parameters of rizatriptan loaded chitosan nanoparticles

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2015
The purpose of present study was to optimize rizatriptan (RZT) chitosan (CS) nanoparticles using ionic gelation method by application of quality by design (QbD) approach. Based on risk assessment, effect of three variables, that is CS %, tripolyphosphate
Ajinath Eknath Shirsat   +1 more
doaj   +1 more source

Investigation of design space for freeze-drying injectable ibuprofen using response surface methodology

open access: yesActa Pharmaceutica, 2021
This study explores the use of a statistical model to build a design space for freeze-drying two formulations with ibuprofen. A 2 × 3 factorial experimental design was used to evaluate independent variables (filling volume and annealing time) and ...
Preskar Maja   +3 more
doaj   +1 more source

Design of Experiment Using Simulation of a Discrete Dynamical System

open access: yesTransactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2016
The topic of the presented paper is a promising approach to achieve optimal Design of Experiment (DoE), i.e. spreading of points within a design domain, using a simulation of a discrete dynamical system of interacting particles within an n-dimensional ...
Mašek Jan   +2 more
doaj   +1 more source

Resonance as a Design Strategy for AI and Social Robots

open access: yesFrontiers in Neurorobotics, 2022
Resonance, a powerful and pervasive phenomenon, appears to play a major role in human interactions. This article investigates the relationship between the physical mechanism of resonance and the human experience of resonance, and considers possibilities ...
James Derek Lomas   +16 more
doaj   +1 more source

Application of I-Optimal Design for Modeling and Optimizing the Operational Parameters of Ibuprofen Granules in Continuous Twin-Screw Wet Granulation

open access: yesBiomedicines, 2023
The continuous twin-screw wet granulation (TSWG) process was investigated and optimized with prediction-oriented I-optimal designs. The I-optimal designs can not only obtain a precise estimation of the parameters that describe the effect of five input ...
Jie Zhao, Geng Tian, Haibin Qu
doaj   +1 more source

A Design Methodology for Space-Time Adapter [PDF]

open access: yes, 2007
This paper presents a solution to efficiently explore the design space of communication adapters. In most digital signal processing (DSP) applications, the overall architecture of the system is significantly affected by communication architecture, so the
Chavet, Cyrille   +3 more
core   +2 more sources

A Design Space of Vision Science Methods for Visualization Research [PDF]

open access: yesIEEE Transactions on Visualization and Computer Graphics, 2020
A growing number of efforts aim to understand what people see when using a visualization. These efforts provide scientific grounding to complement design intuitions, leading to more effective visualization practice.
Madison A. Elliott   +3 more
semanticscholar   +1 more source

Evaluating the suitability of underground space development based on social and economic factors

open access: yesUrban, Planning and Transport Research, 2023
Ma’anshan City, located in the Yangtze River Delta region, is a demonstration city for handling the industrial transfer of the Nanjing, Hefei, and Wanjiang Metropolitan Areas in China.
Yilan Yan, Minghe Sun, Yunpeng Li
doaj   +1 more source

Mission-Driven Inverse Design of Blended Wing Body Aircraft with Machine Learning

open access: yesAerospace
The intent of this work was to investigate the feasibility of developing machine learning models for calculating values of airplane configuration design variables when provided time-series, mission-informed performance data.
Rohan S. Sharma, Serhat Hosder
doaj   +1 more source

Method to Investigate Multi-Axis Release Action of Ski Safety Bindings: A New Approach for Testing in Research and Development

open access: yesFrontiers in Sports and Active Living, 2021
The authors developed and elaborated on a new method to release ski bindings by utilizing an industrial robot to simulate release movement showing a spatial repeatability of ± 0.06 mm.
Florian Nimmervoll   +4 more
doaj   +1 more source

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