The interest to expand group-based studies with single-case experimental design studies in the investigation of the effects of physical exercise in frail older adults: an opinion article. [PDF]
Front Public Health, 2023 Agbangla NF, Caby I, Albinet CT.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Applied SciencesResearch in the field of psychological health care has confirmed that chronic homesickness can exacerbate emotional problems. However, there is a lack of diverse products in the design field that can effectively address the issue of alleviating ...
Ye Zhou, Ken Nah, Suqin Tan
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Systematic review and meta-analysis of the impact of STEM education on students learning outcomes
Frontiers in PsychologyIntroductionSTEM education’s impact on student learning outcomes is nuanced, with differentiated effects across outcome types and academic levels.MethodsThis study uses meta-analysis to systematically analyse 66 experimental and quasi-experimental ...
Xin Cao, Honglei Lu, Qian Wu, Yen Hsu
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Effects of Aronia melanocarpa on Cardiometabolic Diseases: A Systematic Review of Quasi-Design Studies and Randomized Controlled Trials. [PDF]
Rev Diabet Stud, 2022 Christiansen CB +4 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Analysing microbiome intervention design studies: Comparison of alternative multivariate statistical methods. [PDF]
PLoS One, 2021 Khomich M, Måge I, Rud I, Berget I.
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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