Results 81 to 90 of about 4,669,215 (266)

Medications influencing the risk of fall-related injuries in older adults: case-control and case-crossover design studies. [PDF]

BMC Geriatr, 2023
Jung YS, Suh D, Kim E, Park HD, Suh DC, Jung SY.   +5 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Exploring Sustainable Learning Intentions of Employees Using Online Learning Modules of Office Apps Based on User Experience Factors: Using the Adapted UTAUT Model

Applied Sciences
Research on the information module has identified a range of factors in the adoption model that determine their intention to learn sustainably. This research investigates the determinants of employees’ intentions to use an online learning module within ...
Siqin Wang, Ken Nah
doaj   +1 more source

Relation of Food Insecurity and Hemoglobin Level in Preschool Aged Children

Anemia, 2018
Background. The iron deficiency anemia is a worldwide public problem, especially in developing countries, related to increased body needs and inadequate supply of iron from the diet. Objective.
Élida Mara Braga Rocha, Luiz Carlos de Abreu, Amanda Forster Lopes, Claudio Leone, Patrícia Dore Vieira, Italla Maria Pinheiro Bezerra, Sophia Cornbluth Szarfarc   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identifying driving factors influencing summer air temperature and developing a high-resolution temperature map using regression Kriging in Seoul

Geo-spatial Information Science
Urban temperature increases present significant challenges, necessitating the identification of key influencing factors and developing high-resolution temperature maps for effective climate analysis.
Younju Lee, Changyeon Lee
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Perception of public restroom hygiene and Papillomavirus risk among shopping mall users in Ghana

Discover Public Health
Background Despite growing concerns about public restroom hygiene, especially in high-traffic commercial spaces, limited research has explored how users’ perceptions of restroom cleanliness and sanitation conditionsinfluence specific health anxieties ...
Emmanuel Kofi Gyan, Williams Miller Appau, Maxwell Okrah   +2 more
doaj   +1 more source

Air pollution hindering a transit-oriented city: Examining the association of particulate matter concentration with public transit ridership and road traffic in Seoul, South Korea

Journal of Public Transportation
In high-density metropolitan areas prone to air pollution, public transit may be less preferred when air quality is poor due to the difficulty of avoiding outdoor air exposure during their use.
Seung-Nam Kim, Sunwoo Jung, Youngha Joo, Hyungkyoo Kim   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source